Dr Edgar Hartsuiker

Senior Lecturer in Biomedical Sciences (Cancer Biology)

  1. 2011
  2. Published

    Detection of covalent DNA-bound Spo11 and topoisomerase complexes

    Hartsuiker, E. & Tsubouchi, H. (ed.), 28 Apr 2011, DNA recombination: Methods and Protocols. Springer Science and Business Media LLC, p. 65-77

    Research output: Chapter in Book/Report/Conference proceedingChapter

  3. 2010
  4. Published

    Topoisomerase I regulates open chromatin and controls gene expression in vivo

    Durand-Dubief, M., Persson, J., Norman, U., Hartsuiker, E. & Ekwall K., N. V., 7 Jul 2010, In: EMBO Journal. 29, 13, p. 2126 - 2134

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Collaborative Action of Brca1 and CtIP in Elimination of Covalent Modifications from Double-Strand Breaks to Facilitate Subsequent Break Repair

    Nakamura, K., Kogame, T., Oshiumi, H., Shinohara, A., Sumitomo, Y., Agama, K., Pommier, Y., Tsutsui, K. M., Tsutsui, K., Hartsuiker, E., Ogi, T., Takeda, S. & Taniguchi, Y., 22 Jan 2010, In: PLOS Genetics. 6, 1

    Research output: Contribution to journalArticlepeer-review

  6. 2009
  7. Published

    A supramodular FHA/BRCT-Repeat architecture mediates Nbs1 adaptor function in response to DNA damage.

    Lloyd, J., Chapman, J. R., Clapperton, J. A., Haire, L. F., Hartsuiker, E., Li, J., Carr, A. M., Jackson, S. P. & Smerdon, S. J., 2 Oct 2009, In: Cell. 139, 1, p. 100-111

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Screening a genome-wide S.pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.

    Deshpande, G. P., Hayles, J., Hoe, K. L., Kim, D. U., Park, H. O. & Hartsuiker, E., 1 May 2009, In: DNA Repair. 8, 5, p. 672-679

    Research output: Contribution to journalArticlepeer-review

  9. Ctp1CtIP and Rad32Mre11 nuclease activity are required for Rec12Spo11 removal, but Rec12Spo11 removal is dispensable for other MRN-dependent meiotic functions

    Hartsuiker, E., Mizuno, K., Molnar, M., Kohli, J., Ohta, K. & Carr, A. M., Apr 2009, In: Molecular and Cellular Biology. 29, 7, p. 1671-1681 11 p.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Distinct Requirements for the Rad32Mre11 Nuclease and Ctp1CtIP in the Removal of Covalently Bound Topoisomerase I and II from DNA

    Hartsuiker, E., Neale, M. J. & Carr, A. M., 16 Jan 2009, In: Molecular Cell. 33, 1, p. 117-123

    Research output: Contribution to journalArticlepeer-review

  11. 2007
  12. TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks

    El-Khamisy, S. F., Hartsuiker, E. & Caldecott, K. W., 1 Oct 2007, In: DNA Repair. 6, 10, p. 1485-95 11 p.

    Research output: Contribution to journalArticlepeer-review

  13. 2006
  14. Double-strand break repair and homologous recombination in Schizosaccharomyces pombe

    Raji, H. & Hartsuiker, E., 15 Oct 2006, In: Yeast. 23, 13, p. 963-76 14 p.

    Research output: Contribution to journalArticlepeer-review

  15. 2005
  16. Published

    The meiotic recombination hot spot ura4A in Schizosaccharomyces pombe

    Baur, M., Hartsuiker, E., Lehmann, E., Ludin, K., Munz, P. & Kohli, J., Feb 2005, In: Genetics. 169, 2, p. 551-61 11 p.

    Research output: Contribution to journalArticlepeer-review