Dr Rolf Kraehenbuehl

Research Officer

  1. 2023
  2. Published

    Modified Hederagenin Derivatives Demonstrate Ex Vivo Anthelmintic Activity against Fasciola hepatica

    Chakroborty, A., Pritchard, D., Bouillon, M., Cervi, A., Kraehenbuehl, R., Wild, C., Fenn, C., Holdsworth, P., Capner, C., Padalino, G., Forde-Thomas, J. E., Payne, J., Smith, B. G. & Hoffmann, K., 3 Jul 2023, In: Pharmaceutics. 15, 7, 1869.

    Research output: Contribution to journalArticlepeer-review

  3. 2022
  4. Published

    Cyclic guanidine containing amino acids that promote glucocerebrosidase

    Al-Taie, Z. S., Bartholomew, B., Coles, S. J., Evans, D. M., Hollinshead, J., Jones, L. F., Kraehenbuehl, R., Murphy, P. J., Nash, R. J., Penkova, Y. B. & Tizzard, G. J., 24 Sept 2022, In: Tetrahedron. 123, 132959.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Synthesis of (+)-(R)-Tiruchanduramine

    Al-Taie, Z. S., Bartholomew, B., Cartmell, C., Froom, R., Kerr, R. G., Kraehenbuehl, R., Murphy, P., Nash, R. J., Penkova, Y. B. & van Teijlingen, A., 16 Feb 2022, In: Molecules. 27, 4

    Research output: Contribution to journalArticlepeer-review

  6. 2020
  7. Published

    Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication

    Böckemeier, L., Kraehenbuehl, R., Keszthelyi, A., Gasasira, M. U., Vernon, E., Beardmore, R., Broberg Vågbø, C., Chaplin, D., Collins, S., Krokan, H. E., Lambert, S. A. E., Paisz, B. & Hartsuiker, E., 29 May 2020, In: Science Advances. 6, 22, 9 p., eaaz4126.

    Research output: Contribution to journalArticlepeer-review

  8. 2015
  9. Identification of a Class of Protein ADP-Ribosylating Sirtuins in Microbial Pathogens

    Rack, J. G. M., Morra, R., Barkauskaite, E., Kraehenbuehl, R., Ariza, A., Qu, Y., Ortmayer, M., Leidecker, O., Cameron, D. R., Matic, I., Peleg, A. Y., Leys, D., Traven, A. & Ahel, I., 16 Jul 2015, In: Molecular Cell. 59, 2, p. 309-20 12 p.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    UV induced ubiquitination of the yeast Rad4-Rad23 complex promotes survival by regulating cellular dNTP pools

    Zhou, Z., Humphryes, N., van Eijk, P., Waters, R., Yu, S. R., Kraehenbuehl, R., Hartsuiker, E. & Reed, S. H., 6 Jul 2015, In: Nucleic Acids Research. 43, 15, p. 7360-7370

    Research output: Contribution to journalArticlepeer-review

  11. 2011
  12. DNA Repair Factor APLF Is a Histone Chaperone

    Kraehenbuehl, R., 2011, In: Molecular Cell. 41

    Research output: Contribution to journalArticlepeer-review

  13. Identification of Macrodomain Proteins as NovelO-Acetyl-ADP-ribose Deacetylases

    Kraehenbuehl, R., 2011, In: Journal of Biological Chemistry.

    Research output: Contribution to journalArticlepeer-review

  14. Structure of an aprataxin neurodegenerative disease

    Kraehenbuehl, R., 2011, In: Nature Structural Molecular Biology.

    Research output: Contribution to journalArticlepeer-review

  15. 2009
  16. Published

    Flipping of alkylated DNA damage bridges base and nucleotide excision repair

    Tubbs, J. L., Latypov, V., Kanugula, S., Butt, A., Melikishvili, M., Kraehenbuehl, R., Fleck, O., Marriott, A., Watson, A. J., Verbeek, B., McGown, G., Thorncroft, M., Santibanez-Koref, M. F., Millington, C., Arvai, A. S., Kroeger, M. D., Peterson, L. A., Williams, D. M., Fried, M. G., Margison, G. P., Pegg, A. E. & Tainer, J. A., 11 Jun 2009, In: Nature. 459, p. 808-813

    Research output: Contribution to journalArticlepeer-review

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