Cyclic guanidine containing amino acids that promote glucocerebrosidase
Research output: Contribution to journal › Article › peer-review
Electronic versions
Novel cyclic guanidine containing amino acids (S)-1, 2 and 3 were prepared from l-serine 5. (S)-2-Imino-3-methylimidazolidine-4-carboxylic acid hydrochloride salt 2. HCl and (3S, 6S)-3,6-bis(hydroxymethyl)-1,4-dimethylpiperazine-2,5-dione 15 showed in vitro promotion of the enzyme glucocerebrosidase.
Keywords
- Cyclic guanidines, Glycosidase inhibitors, Glycosidase promoters, -methylation
| Original language | English |
|---|---|
| Article number | 132959 |
| Journal | Tetrahedron |
| Volume | 123 |
| DOIs | |
| Publication status | Published - 24 Sept 2022 |