Cyclic guanidine containing amino acids that promote glucocerebrosidase
Research output: Contribution to journal › Article › peer-review
Electronic versions
Novel cyclic guanidine containing amino acids (S)-1, 2 and 3 were prepared from l-serine 5. (S)-2-Imino-3-methylimidazolidine-4-carboxylic acid hydrochloride salt 2. HCl and (3S, 6S)-3,6-bis(hydroxymethyl)-1,4-dimethylpiperazine-2,5-dione 15 showed in vitro promotion of the enzyme glucocerebrosidase.
Keywords
- Cyclic guanidines, Glycosidase inhibitors, Glycosidase promoters, -methylation
Original language | English |
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Article number | 132959 |
Journal | Tetrahedron |
Volume | 123 |
DOIs | |
Publication status | Published - 24 Sept 2022 |