3D Pattern of brain abnormalisiteis in William syndrome visualized using tensor-based morphometry

Research output: Contribution to journalArticlepeer-review

Electronic versions

  • Ming-Chang Chiang
  • Allan Reiss
  • Agatha D Lee
  • Ursula Bellugi
  • Albert M. Galaburda
  • Julie R. Korenberg
  • Debra Mills
  • Arthur W. Toga
  • Paul M. Thompson
Williams syndrome (WS) is a neurodevelopmental disorder associated with deletion of ∼ 20 contiguous genes in chromosome band 7q11.23. Individuals with WS exhibit mild to moderate mental retardation, but are relatively more proficient in specific language and musical abilities. We used tensor-based morphometry (TBM) to visualize the complex pattern of gray/white matter reductions in WS, based on fluid registration of structural brain images.
Original languageEnglish
Pages (from-to)1096-1109
Number of pages16
JournalNeuroimage
Volume36
Issue number4
DOIs
Publication statusPublished - 2007
View graph of relations