Cell detection and discrimination by a microfluidic-integrated broadband microchamber
Research output: Contribution to conference › Paper
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2014. 695-698 Paper presented at 44th European Microwave Conference (EuMC), Rome, 6-9 Oct 2014.
Research output: Contribution to conference › Paper
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T1 - Cell detection and discrimination by a microfluidic-integrated broadband microchamber
AU - Denzi, A.
AU - Apollonio, F.
AU - Liberti, M.
AU - Merla, C.
AU - Ning, Y.
AU - Multari, C.
AU - Palego, C.
PY - 2014/10/5
Y1 - 2014/10/5
N2 - In the last years, the development of broadband microwave sensors for cell detection has become a great challenge. In this work, a broadband microchamber integrated with microfluidics is used for cell detection in the GHz range. Measurements of scattering parameters have been carried out, demonstrating the capability of the device to discriminate different number of cells between the electrodes. Stable and reliable results on Jurkat cell solutions have been achieved. An equivalent circuit model, dependent on the number of cells trapped within the channel, has been extracted from the experimental data sets. We demonstrate the possibility to detect and isolate the electrical contribution of biological cells.
AB - In the last years, the development of broadband microwave sensors for cell detection has become a great challenge. In this work, a broadband microchamber integrated with microfluidics is used for cell detection in the GHz range. Measurements of scattering parameters have been carried out, demonstrating the capability of the device to discriminate different number of cells between the electrodes. Stable and reliable results on Jurkat cell solutions have been achieved. An equivalent circuit model, dependent on the number of cells trapped within the channel, has been extracted from the experimental data sets. We demonstrate the possibility to detect and isolate the electrical contribution of biological cells.
U2 - 10.1109/EuMC.2014.6986529
DO - 10.1109/EuMC.2014.6986529
M3 - Paper
SP - 695
EP - 698
T2 - 44th European Microwave Conference (EuMC), Rome, 6-9 Oct 2014
Y2 - 3 January 0001
ER -