Compact Nanosecond Bipolar Pulse Generator for On-chip Modulation of Biological Response
Research output: Contribution to conference › Paper › peer-review
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2021. Paper presented at URSI GASS 2021, Rome, Italy.
Research output: Contribution to conference › Paper › peer-review
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T1 - Compact Nanosecond Bipolar Pulse Generator for On-chip Modulation of Biological Response
AU - Davies, Ilan
AU - Karim, Nissar
AU - Eltokhy, Amira
AU - Carr, Lynn
AU - Hancock, Chris
AU - Palego, Cristiano
AU - Durmaz, Emre C.
AU - Kaynak, Canan Baristiran
AU - Kaynak, Mehmet
AU - Pothier, Arnaud
AU - Arnaud-Cosmos, Delia
AU - Leveque, Philippe
PY - 2021/8/28
Y1 - 2021/8/28
N2 - The SUMCASTEC project aims to isolate and neutralize brain cancer stem-like cells (CSC) using electromagnetic stimulation [1]. We present a new compact nanosecond pulse electric field generator that can deliver 500 V, 10 ns bipolar pulses that was developed in the frame of the project. The generator is optimized for driving miniaturized lab-on-chip (LOC) applicators thus supporting modulation of cell response, with relatively lower input voltage, and higher field uniformity than in conventional dish-based or cuvette applicators. The preliminary experimental results demonstrate modulation of CSCs response to nanosecond pulses through field reversal are presented.
AB - The SUMCASTEC project aims to isolate and neutralize brain cancer stem-like cells (CSC) using electromagnetic stimulation [1]. We present a new compact nanosecond pulse electric field generator that can deliver 500 V, 10 ns bipolar pulses that was developed in the frame of the project. The generator is optimized for driving miniaturized lab-on-chip (LOC) applicators thus supporting modulation of cell response, with relatively lower input voltage, and higher field uniformity than in conventional dish-based or cuvette applicators. The preliminary experimental results demonstrate modulation of CSCs response to nanosecond pulses through field reversal are presented.
M3 - Paper
T2 - URSI GASS 2021
Y2 - 28 August 2021 through 4 September 2021
ER -