fMRI activation during observation of others' reach errors
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In: Journal of Cognitive Neurosience, Vol. 22, No. 7, 07.2010, p. 1493-1503.
Research output: Contribution to journal › Article › peer-review
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T1 - fMRI activation during observation of others' reach errors
AU - Malfait, Nicole
AU - Valyear, Kenneth F
AU - Culham, Jody C
AU - Anton, Jean-Luc
AU - Brown, Liana E
AU - Gribble, Paul L
PY - 2010/7
Y1 - 2010/7
N2 - When exposed to novel dynamical conditions (e.g., externally imposed forces), neurologically intact subjects easily adjust motor commands on the basis of their own reaching errors. Subjects can also benefit from visual observation of others' kinematic errors. Here, using fMRI, we scanned subjects watching movies depicting another person learning to reach in a novel dynamic environment created by a robotic device. Passive observation of reaching movements (whether or not they were perturbed by the robot) was associated with increased activation in fronto-parietal regions that are normally recruited in active reaching. We found significant clusters in parieto-occipital cortex, intraparietal sulcus, as well as in dorsal premotor cortex. Moreover, it appeared that part of the network that has been shown to be engaged in processing self-generated reach error is also involved in observing reach errors committed by others. Specifically, activity in left intraparietal sulcus and left dorsal premotor cortex, as well as in right cerebellar cortex, was modulated by the amplitude of observed kinematic errors.
AB - When exposed to novel dynamical conditions (e.g., externally imposed forces), neurologically intact subjects easily adjust motor commands on the basis of their own reaching errors. Subjects can also benefit from visual observation of others' kinematic errors. Here, using fMRI, we scanned subjects watching movies depicting another person learning to reach in a novel dynamic environment created by a robotic device. Passive observation of reaching movements (whether or not they were perturbed by the robot) was associated with increased activation in fronto-parietal regions that are normally recruited in active reaching. We found significant clusters in parieto-occipital cortex, intraparietal sulcus, as well as in dorsal premotor cortex. Moreover, it appeared that part of the network that has been shown to be engaged in processing self-generated reach error is also involved in observing reach errors committed by others. Specifically, activity in left intraparietal sulcus and left dorsal premotor cortex, as well as in right cerebellar cortex, was modulated by the amplitude of observed kinematic errors.
KW - Adult
KW - Brain Mapping
KW - Cerebellar Cortex
KW - Female
KW - Humans
KW - Magnetic Resonance Imaging
KW - Male
KW - Motor Cortex
KW - Nerve Net
KW - Observation
KW - Occipital Lobe
KW - Parietal Lobe
KW - Photic Stimulation
KW - Psychomotor Performance
KW - Young Adult
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1162/jocn.2009.21281
DO - 10.1162/jocn.2009.21281
M3 - Article
C2 - 19580392
VL - 22
SP - 1493
EP - 1503
JO - Journal of Cognitive Neurosience
JF - Journal of Cognitive Neurosience
SN - 1530-8898
IS - 7
ER -