Human premotor areas parse sequences into their spatial and temporal features

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Human premotor areas parse sequences into their spatial and temporal features. / Kornysheva, Katja; Diedrichsen, Jörn.
In: Elife, Vol. 3, 12.08.2014, p. e03043.

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Kornysheva K, Diedrichsen J. Human premotor areas parse sequences into their spatial and temporal features. Elife. 2014 Aug 12;3:e03043. doi: 10.7554/eLife.03043

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Kornysheva, Katja ; Diedrichsen, Jörn. / Human premotor areas parse sequences into their spatial and temporal features. In: Elife. 2014 ; Vol. 3. pp. e03043.

RIS

TY - JOUR

T1 - Human premotor areas parse sequences into their spatial and temporal features

AU - Kornysheva, Katja

AU - Diedrichsen, Jörn

N1 - Copyright © 2014, Kornysheva and Diedrichsen.

PY - 2014/8/12

Y1 - 2014/8/12

N2 - Skilled performance is characterized by precise and flexible control of movement sequences in space and time. Recent theories suggest that integrated spatio-temporal trajectories are generated by intrinsic dynamics of motor and premotor networks. This contrasts with behavioural advantages that emerge when a trained spatial or temporal feature of sequences is transferred to a new spatio-temporal combination arguing for independent neural representations of these sequence features. We used a new fMRI pattern classification approach to identify brain regions with independent vs integrated representations. A distinct regional dissociation within motor areas was revealed: whereas only the contralateral primary motor cortex exhibited unique patterns for each spatio-temporal sequence combination, bilateral premotor areas represented spatial and temporal features independently of each other. These findings advocate a unique function of higher motor areas for flexible recombination and efficient encoding of complex motor behaviours.

AB - Skilled performance is characterized by precise and flexible control of movement sequences in space and time. Recent theories suggest that integrated spatio-temporal trajectories are generated by intrinsic dynamics of motor and premotor networks. This contrasts with behavioural advantages that emerge when a trained spatial or temporal feature of sequences is transferred to a new spatio-temporal combination arguing for independent neural representations of these sequence features. We used a new fMRI pattern classification approach to identify brain regions with independent vs integrated representations. A distinct regional dissociation within motor areas was revealed: whereas only the contralateral primary motor cortex exhibited unique patterns for each spatio-temporal sequence combination, bilateral premotor areas represented spatial and temporal features independently of each other. These findings advocate a unique function of higher motor areas for flexible recombination and efficient encoding of complex motor behaviours.

KW - Adult

KW - Brain Mapping

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Motor Cortex

KW - Movement

KW - Prefrontal Cortex

KW - Psychomotor Performance

KW - Space Perception

KW - Time Perception

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.7554/eLife.03043

DO - 10.7554/eLife.03043

M3 - Article

C2 - 25117541

VL - 3

SP - e03043

JO - Elife

JF - Elife

SN - 2050-084X

ER -