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Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena.

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Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. / Westbury, Michael V.; Hartmann, Stefanie; Barlow, Axel et al.
In: Science Advances, Vol. 6, No. 11, 13.03.2020.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Westbury, MV, Hartmann, S, Barlow, A, Preick, M, Ridush, B, Nagel, D, Rathgeber, T, Ziegler, R, Baryshnikov, G, Sheng, G, Ludwig, A, Wiesel, I, Dalén, L, Bibi, F, Werdelin, L, Heller, R & Hofreiter, M 2020, 'Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena.', Science Advances, vol. 6, no. 11. https://doi.org/https://advances.sciencemag.org/content/6/11/eaay0456

APA

Westbury, M. V., Hartmann, S., Barlow, A., Preick, M., Ridush, B., Nagel, D., Rathgeber, T., Ziegler, R., Baryshnikov, G., Sheng, G., Ludwig, A., Wiesel, I., Dalén, L., Bibi, F., Werdelin, L., Heller, R., & Hofreiter, M. (2020). Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. Science Advances, 6(11). https://doi.org/https://advances.sciencemag.org/content/6/11/eaay0456

CBE

Westbury MV, Hartmann S, Barlow A, Preick M, Ridush B, Nagel D, Rathgeber T, Ziegler R, Baryshnikov G, Sheng G, et al. 2020. Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. Science Advances. 6(11). https://doi.org/https://advances.sciencemag.org/content/6/11/eaay0456

MLA

Westbury, Michael V. et al. "Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena.". Science Advances. 2020. 6(11). https://doi.org/https://advances.sciencemag.org/content/6/11/eaay0456

VancouverVancouver

Westbury MV, Hartmann S, Barlow A, Preick M, Ridush B, Nagel D et al. Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. Science Advances. 2020 Mar 13;6(11). doi: https://advances.sciencemag.org/content/6/11/eaay0456

Author

Westbury, Michael V. ; Hartmann, Stefanie ; Barlow, Axel et al. / Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. In: Science Advances. 2020 ; Vol. 6, No. 11.

RIS

TY - JOUR

T1 - Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena.

AU - Westbury, Michael V.

AU - Hartmann, Stefanie

AU - Barlow, Axel

AU - Preick, Michaela

AU - Ridush, Brogdan

AU - Nagel, Doris

AU - Rathgeber, Thomas

AU - Ziegler, Reinhard

AU - Baryshnikov, Gennady

AU - Sheng, Guilian

AU - Ludwig, Arne

AU - Wiesel, Ingrid

AU - Dalén, Love

AU - Bibi, Faysal

AU - Werdelin, Lars

AU - Heller, Rasmus

AU - Hofreiter, Michael

PY - 2020/3/13

Y1 - 2020/3/13

N2 - The genus Crocuta (African spotted and Eurasian cave hyenas) includes several closely related extinct and extant lineages. The relationships among these lineages, however, are contentious. Through the generation of population-level paleogenomes from late Pleistocene Eurasian cave hyena and genomes from modern African spotted hyena, we reveal the cross-continental evolutionary relationships between these enigmatic hyena lineages. We find a deep divergence (~2.5 Ma) between African and Eurasian Crocuta populations, suggesting that ancestral Crocuta left Africa around the same time as early Homo. Moreover, we find discordance between nuclear and mitochondrial phylogenies and evidence for bidirectional gene flow between African and Eurasian Crocuta after the lineages split, which may have complicated prior taxonomic classifications. Last, we find a number of introgressed loci that attained high frequencies within the recipient lineage, suggesting some level of adaptive advantage from admixture.

AB - The genus Crocuta (African spotted and Eurasian cave hyenas) includes several closely related extinct and extant lineages. The relationships among these lineages, however, are contentious. Through the generation of population-level paleogenomes from late Pleistocene Eurasian cave hyena and genomes from modern African spotted hyena, we reveal the cross-continental evolutionary relationships between these enigmatic hyena lineages. We find a deep divergence (~2.5 Ma) between African and Eurasian Crocuta populations, suggesting that ancestral Crocuta left Africa around the same time as early Homo. Moreover, we find discordance between nuclear and mitochondrial phylogenies and evidence for bidirectional gene flow between African and Eurasian Crocuta after the lineages split, which may have complicated prior taxonomic classifications. Last, we find a number of introgressed loci that attained high frequencies within the recipient lineage, suggesting some level of adaptive advantage from admixture.

U2 - https://advances.sciencemag.org/content/6/11/eaay0456

DO - https://advances.sciencemag.org/content/6/11/eaay0456

M3 - Article

VL - 6

JO - Science Advances

JF - Science Advances

SN - 2375-2548

IS - 11

ER -