TY - JOUR

T1 - Impaired integration of object knowledge and visual input in a case of ventral simultanagnosia with bilateral damage to area V4

AU - Leek, C.

AU - D-Avossa, G.G.

AU - Tainturier, M.

AU - Leek, E.C.

AU - d'Avossa, G.

AU - Tainturier, M.J.

AU - Roberts, D.J.

AU - Yuen, S.L.

AU - Hu, M.

AU - Rafal, R.D.

PY - 2012/11/19

Y1 - 2012/11/19

N2 - This study examines how brain damage can affect the cognitive processes that support the integration of sensory input and prior knowledge during shape perception. It is based on the first detailed study of acquired ventral simultanagnosia, which was found in a patient (M.T.) with posterior occipitotemporal lesions encompassing V4 bilaterally. Despite showing normal object recognition for single items in both accuracy and response times (RTs), and intact low-level vision assessed across an extensive battery of tests, M.T. was impaired in object identification with overlapping figures displays. Task performance was modulated by familiarity: Unlike controls, M.T. was faster with overlapping displays of abstract shapes than with overlapping displays of common objects. His performance with overlapping common object displays was also influenced by both the semantic relatedness and visual similarity of the display items. These findings challenge claims that visual perception is driven solely by feedforward mechanisms and show how brain damage can selectively impair high-level perceptual processes supporting the integration of stored knowledge and visual sensory input.

AB - This study examines how brain damage can affect the cognitive processes that support the integration of sensory input and prior knowledge during shape perception. It is based on the first detailed study of acquired ventral simultanagnosia, which was found in a patient (M.T.) with posterior occipitotemporal lesions encompassing V4 bilaterally. Despite showing normal object recognition for single items in both accuracy and response times (RTs), and intact low-level vision assessed across an extensive battery of tests, M.T. was impaired in object identification with overlapping figures displays. Task performance was modulated by familiarity: Unlike controls, M.T. was faster with overlapping displays of abstract shapes than with overlapping displays of common objects. His performance with overlapping common object displays was also influenced by both the semantic relatedness and visual similarity of the display items. These findings challenge claims that visual perception is driven solely by feedforward mechanisms and show how brain damage can selectively impair high-level perceptual processes supporting the integration of stored knowledge and visual sensory input.

U2 - 10.1080/02643294.2012.752724

DO - 10.1080/02643294.2012.752724

M3 - Article

VL - 29

SP - 569

EP - 583

JO - Cognitive Neuropsychology

JF - Cognitive Neuropsychology

SN - 0264-3294

IS - 7-8

ER -