Label-free non-invasive subwavelength-resolution imaging using yeast cells as biological lenses
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- boe-12-11-7113
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DOI
There is a growing interest to use live cells to replace the widely used non-biological microsphere lenses. In this work, we demonstrate the use of yeast cells for such imaging purpose. Using fiber-based optical trapping technique, we trap a chain of three yeast cells and bring them to the vicinity of imaging objects. These yeast cells work as near-field magnifying lenses and simultaneously pick up the sub-diffraction information of the nanoscale objects under each cell and project them into the far-field. The experimental results demonstrated that Blu-ray disc of 100 nm feature can be clearly resolved in a parallel manner by each cell.
| Original language | English |
|---|---|
| Pages (from-to) | 7113-7121 |
| Number of pages | 9 |
| Journal | Biomedical optics express |
| Volume | 12 |
| Issue number | 11 |
| Early online date | 26 Oct 2021 |
| DOIs | |
| Publication status | Published - 1 Nov 2021 |
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