Electronic versions



  • Maria-Elena Stefanou
    University of Freiburg
  • N.M. Dundon
    University of California, Santa Barbara
  • Patricia Bestelmeyer
  • Chara Ioannou
    University of Freiburg
  • Stephan Bender
    University of Cologne
  • M. Biscaldi
    University of Freiburg
  • Nikolaos Smyrnis
    University Mental Health Research Institute, Athens
  • Christoph Klein
    University of Freiburg
Sensory processing deficits and altered long-range connectivity putatively underlie Multisensory Integration (MSI) deficits in Autism Spectrum Disorder (ASD). The present study set out to investigate non-social MSI stimuli and their electrophysiological correlates in young neurotypical adolescents and adolescents with ASD. We report robust MSI effects at behavioural and electrophysiological levels. Both groups demonstrated normal behavioural
MSI. However, at the neurophysiological level, the ASD group showed less MSI-related reduction of the visual P100 latency, greater MSI-related slowing of the auditory P200 and an overall temporally delayed and spatially constrained onset of MSI. Given the task design and patient sample, and the age of our participants, we argue that electro-cortical indices of MSI deficits in ASD: (a) can be detected in early-adolescent ASD, (b) occur at early stages of perceptual processing, (c) can possibly be compensated by later attentional processes, (d)
thus leading to normal MSI at the behavioural level.

Original languageEnglish
Article number16157
JournalScientific Reports
Issue number1
Publication statusPublished - 30 Sep 2020

Total downloads

No data available
View graph of relations