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Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra

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Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra. / O'Neill, J.S.; Lee, K.D.; Zhang, L. et al.
In: Current Biology, 20.04.2015, p. R326-R327.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

O'Neill, JS, Lee, KD, Zhang, L, Feeney, K, Webster, SG, Blades, MJ, Kyriacou, CP, Hastings, MH & Wilcockson, DC 2015, 'Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra', Current Biology, pp. R326-R327. https://doi.org/10.1016/j.cub.2015.02.052

APA

O'Neill, J. S., Lee, K. D., Zhang, L., Feeney, K., Webster, S. G., Blades, M. J., Kyriacou, C. P., Hastings, M. H., & Wilcockson, D. C. (2015). Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra. Current Biology, R326-R327. https://doi.org/10.1016/j.cub.2015.02.052

CBE

O'Neill JS, Lee KD, Zhang L, Feeney K, Webster SG, Blades MJ, Kyriacou CP, Hastings MH, Wilcockson DC. 2015. Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra. Current Biology. R326-R327. https://doi.org/10.1016/j.cub.2015.02.052

MLA

O'Neill, J.S. et al. "Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra". Current Biology. 2015, R326-R327. https://doi.org/10.1016/j.cub.2015.02.052

VancouverVancouver

O'Neill JS, Lee KD, Zhang L, Feeney K, Webster SG, Blades MJ et al. Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra. Current Biology. 2015 Apr 20;R326-R327. doi: 10.1016/j.cub.2015.02.052

Author

O'Neill, J.S. ; Lee, K.D. ; Zhang, L. et al. / Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra. In: Current Biology. 2015 ; pp. R326-R327.

RIS

TY - JOUR

T1 - Metabolic molecular markers of the tidal clock in the marine crustacean Eurydice pulchra

AU - O'Neill, J.S.

AU - Lee, K.D.

AU - Zhang, L.

AU - Feeney, K.

AU - Webster, S.G.

AU - Blades, M.J.

AU - Kyriacou, C.P.

AU - Hastings, M.H.

AU - Wilcockson, D.C.

PY - 2015/4/20

Y1 - 2015/4/20

N2 - In contrast to the well mapped molecular orchestration of circadian timekeeping in terrestrial organisms, the mechanisms that direct tidal and lunar rhythms in marine species are entirely unknown. Using a combination of biochemical and molecular approaches we have identified a series of metabolic markers of the tidal clock of the intertidal isopod Eurydice pulchra. Specifically, we show that the overoxidation of peroxiredoxin (PRX), a conserved marker of circadian timekeeping in terrestrial eukaryotes [1], follows a circatidal (approximately 12.4 hours) pattern in E. pulchra, in register with the tidal pattern of swimming. In parallel, we show that mitochondrially encoded genes are expressed with a circatidal rhythm. Together, these findings demonstrate that PRX overoxidation rhythms are not intrinsically circadian; rather they appear to resonate with the dominant metabolic cycle of an organism, regardless of its frequency. Moreover, they provide the first molecular leads for dissecting the tidal clockwork.

AB - In contrast to the well mapped molecular orchestration of circadian timekeeping in terrestrial organisms, the mechanisms that direct tidal and lunar rhythms in marine species are entirely unknown. Using a combination of biochemical and molecular approaches we have identified a series of metabolic markers of the tidal clock of the intertidal isopod Eurydice pulchra. Specifically, we show that the overoxidation of peroxiredoxin (PRX), a conserved marker of circadian timekeeping in terrestrial eukaryotes [1], follows a circatidal (approximately 12.4 hours) pattern in E. pulchra, in register with the tidal pattern of swimming. In parallel, we show that mitochondrially encoded genes are expressed with a circatidal rhythm. Together, these findings demonstrate that PRX overoxidation rhythms are not intrinsically circadian; rather they appear to resonate with the dominant metabolic cycle of an organism, regardless of its frequency. Moreover, they provide the first molecular leads for dissecting the tidal clockwork.

U2 - 10.1016/j.cub.2015.02.052

DO - 10.1016/j.cub.2015.02.052

M3 - Article

SP - R326-R327

JO - Current Biology

JF - Current Biology

SN - 0960-9822

ER -