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DOI

  • Paula Ghaneh
    University of Liverpool
  • Robert Hanson
    University of Liverpool
  • Andrew Titman
    Lancaster University
  • Gill Lancaster
    Lancaster University
  • Catrin Plumpton
  • Huw Lloyd-Williams
  • Seow Tien Yeo
  • Rhiannon Edwards
  • Colin Johnson
    University of Southampton
  • Mohammed Abu Hilal
    University Hospital Southampton NHS Foundation Trust
  • Antony Higginson
    Portsmouth Hospitals NHS Trust
  • Tom Armstrong
    University Hospital Southampton NHS Foundation Trust
  • Andrew Smith
    Leeds Teaching Hospitals NHS Trust
  • Andrew Scarsbrook
    Leeds Teaching Hospitals NHS Trust
  • Colin McKay
    NHS Greater Glasgow and Clyde
  • Ross Carter
    NHS Greater Glasgow and Clyde
  • Robert Sutcliffe
    University Hospitals Birmingham NHS Foundation Trust
  • Simon Bramhall
    Wye Valley NHS Trust
  • Hemant Kocher
    Barts and the London School of Medicine and Dentistry
  • David Cunningham
    Royal Marsden NHS Foundation Trust
  • Stephen Pereira
    University College London Hospitals NHS Foundation Trust
  • Brian Davidson
    Royal Free London NHS Foundation Trust
  • David Chang
    East Lancashire Hospitals NHS Trust
  • Saboor Khan
    University Hospitals Coventry and Warwickshire NHS Trust
  • Ian Zealley
    NHS Tayside
  • Debashis Sarker
    King's College Hospital NHS Foundation Trust
  • Bilal Al Sarireh
    Abertawe Bro Morgannwg University Health Board
  • Richard Charnley
    Newcastle Hospitals NHS Foundation Trust
  • Dileep Lobo
    University of Nottingham
  • Marianne Nicolson
    NHS Grampian
  • Christopher Halloran
    University of Liverpool
  • Michael Raraty
    Royal Liverpool and Broadgreen University Hospitals NHS Trust
  • Robert Sutton
    Royal Liverpool and Broadgreen University Hospitals NHS Trust
  • Sobhan Vinjamuri
    Royal Liverpool and Broadgreen University Hospitals NHS Trust
  • Jonathan Evans
    Royal Liverpool and Broadgreen University Hospitals NHS Trust
  • Fiona Campbell
    Royal Liverpool and Broadgreen University Hospitals NHS Trust
  • Jon Deeks
    University of Birmingham
  • Bal Sanghera
    Mount Vernon Hospital
  • Wai-Lup Wong
    Mount Vernon Hospital
  • John Neoptolemos
    University of Liverpool
Overall survival for patients with pancreatic cancer remains poor. Challenges in the care of patients with pancreatic cancer include late presentation and difficulties in early diagnosis. Standard diagnosis of patients with pancreatic cancer consists of a computed tomography (CT) scan, a magnetic resonance imaging (MRI) scan and camera tests. Additional imaging tests may be able to identify pancreatic cancer and the stage of disease more effectively. This would mean that patients would receive the most appropriate treatment at the right time. Positron emission tomography (PET)/CT is a nuclear medicine scan that gives a functional image of the body along with the CT scan. This study used PET/CT in patients with suspected pancreatic cancer as well as standard tests to see if the diagnosis and treatment of these patients could be improved. In total, 550 patients had PET/CT scans. The PET/CT added significantly to the accuracy of standard tests, improving the diagnosis of pancreatic cancer. PET/CT influenced the management of 45% of patients. PET/CT was able to correctly stage the extent of the tumours in a greater number of patients than standard diagnostic tests. This meant that the addition of PET/CT changed the management of these patients to more appropriate therapies. The biggest benefit was seen for those patients who were due to have surgery. We calculated that the use of PET/CT was likely to be good value for money for the NHS. This study suggests that PET/CT is likely to be beneficial in the diagnosis and management of patients with suspected pancreatic cancer.
Original languageEnglish
Number of pages148
JournalHealth Technology Assessment
Volume22
Issue number7
DOIs
Publication statusPublished - 6 Feb 2018

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