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The ancient evolutionary history of polyomaviruses

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The ancient evolutionary history of polyomaviruses. / Buck, Christopher, B; Van Doorslaer, Konread; Peretti, Alberto et al.
In: PLoS Pathogens, Vol. 12, No. 4, e1005574, 19.04.2016.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Buck, CB, Van Doorslaer, K, Peretti, A, Geoghegan, EM, Tisza, MJ, An, P, Katz, JP, Pipas, JM, McBride, AA, Camus, AC, McDermott, AJ, Dill, JA, Delwart, E, Ng, TFF, Farkas, K, Austin, C, Kraberger, S, Davison, W, Pastrana, FV & Varsani, A 2016, 'The ancient evolutionary history of polyomaviruses', PLoS Pathogens, vol. 12, no. 4, e1005574. https://doi.org/10.1371/journal.ppat.1005574

APA

Buck, C. B., Van Doorslaer, K., Peretti, A., Geoghegan, E. M., Tisza, M. J., An, P., Katz, J. P., Pipas, J. M., McBride, A. A., Camus, A. C., McDermott, A. J., Dill, J. A., Delwart, E., Ng, T. F. F., Farkas, K., Austin, C., Kraberger, S., Davison, W., Pastrana, F. V., & Varsani, A. (2016). The ancient evolutionary history of polyomaviruses. PLoS Pathogens, 12(4), Article e1005574. https://doi.org/10.1371/journal.ppat.1005574

CBE

Buck CB, Van Doorslaer K, Peretti A, Geoghegan EM, Tisza MJ, An P, Katz JP, Pipas JM, McBride AA, Camus AC, et al. 2016. The ancient evolutionary history of polyomaviruses. PLoS Pathogens. 12(4):Article e1005574. https://doi.org/10.1371/journal.ppat.1005574

MLA

Buck, Christopher, B et al. "The ancient evolutionary history of polyomaviruses". PLoS Pathogens. 2016. 12(4). https://doi.org/10.1371/journal.ppat.1005574

VancouverVancouver

Buck CB, Van Doorslaer K, Peretti A, Geoghegan EM, Tisza MJ, An P et al. The ancient evolutionary history of polyomaviruses. PLoS Pathogens. 2016 Apr 19;12(4):e1005574. doi: 10.1371/journal.ppat.1005574

Author

Buck, Christopher, B ; Van Doorslaer, Konread ; Peretti, Alberto et al. / The ancient evolutionary history of polyomaviruses. In: PLoS Pathogens. 2016 ; Vol. 12, No. 4.

RIS

TY - JOUR

T1 - The ancient evolutionary history of polyomaviruses

AU - Buck, Christopher, B

AU - Van Doorslaer, Konread

AU - Peretti, Alberto

AU - Geoghegan, Eileen M.

AU - Tisza, Michael J.

AU - An, Ping

AU - Katz, Joshua P.

AU - Pipas, James M.

AU - McBride, Alison A.

AU - Camus, Alvin C.

AU - McDermott, Alexa J.

AU - Dill, Jennifer A.

AU - Delwart, Eric

AU - Ng, Terry F. F.

AU - Farkas, Kata

AU - Austin, Charlotte

AU - Kraberger, Simona

AU - Davison, William

AU - Pastrana, Fiana V.

AU - Varsani, Arvind

PY - 2016/4/19

Y1 - 2016/4/19

N2 - Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches to identify and characterize polyomavirus sequences associated with fish and arthropods. Analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years. Phylogenetic analyses of individual polyomavirus genes suggest that some modern polyomavirus species arose after ancient recombination events involving distantly related polyomavirus lineages. The improved evolutionary model provides a useful platform for developing a more accurate taxonomic classification system for the viral family Polyomaviridae.

AB - Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches to identify and characterize polyomavirus sequences associated with fish and arthropods. Analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years. Phylogenetic analyses of individual polyomavirus genes suggest that some modern polyomavirus species arose after ancient recombination events involving distantly related polyomavirus lineages. The improved evolutionary model provides a useful platform for developing a more accurate taxonomic classification system for the viral family Polyomaviridae.

U2 - 10.1371/journal.ppat.1005574

DO - 10.1371/journal.ppat.1005574

M3 - Article

VL - 12

JO - PLoS Pathogens

JF - PLoS Pathogens

IS - 4

M1 - e1005574

ER -