The economic burden of advanced Parkinson’s disease: an analysis of a UK patient dataset

Research output: Contribution to journalArticlepeer-review

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The economic burden of advanced Parkinson’s disease: an analysis of a UK patient dataset. / Findley, Leslie J; Wood, Eifiona; Lowin, Julia et al.
In: Journal of Medical Economics, Vol. 14, No. 1, 17.01.2011, p. 130-9.

Research output: Contribution to journalArticlepeer-review

HarvardHarvard

Findley, LJ, Wood, E, Lowin, J, Roeder, C, Bergman, A & Schifflers, M 2011, 'The economic burden of advanced Parkinson’s disease: an analysis of a UK patient dataset', Journal of Medical Economics, vol. 14, no. 1, pp. 130-9. https://doi.org/10.3111/13696998.2010.551164

APA

Findley, L. J., Wood, E., Lowin, J., Roeder, C., Bergman, A., & Schifflers, M. (2011). The economic burden of advanced Parkinson’s disease: an analysis of a UK patient dataset. Journal of Medical Economics, 14(1), 130-9. https://doi.org/10.3111/13696998.2010.551164

CBE

Findley LJ, Wood E, Lowin J, Roeder C, Bergman A, Schifflers M. 2011. The economic burden of advanced Parkinson’s disease: an analysis of a UK patient dataset. Journal of Medical Economics. 14(1):130-9. https://doi.org/10.3111/13696998.2010.551164

MLA

VancouverVancouver

Findley LJ, Wood E, Lowin J, Roeder C, Bergman A, Schifflers M. The economic burden of advanced Parkinson’s disease: an analysis of a UK patient dataset. Journal of Medical Economics. 2011 Jan 17;14(1):130-9. doi: 10.3111/13696998.2010.551164

Author

Findley, Leslie J ; Wood, Eifiona ; Lowin, Julia et al. / The economic burden of advanced Parkinson’s disease : an analysis of a UK patient dataset. In: Journal of Medical Economics. 2011 ; Vol. 14, No. 1. pp. 130-9.

RIS

TY - JOUR

T1 - The economic burden of advanced Parkinson’s disease

T2 - an analysis of a UK patient dataset

AU - Findley, Leslie J

AU - Wood, Eifiona

AU - Lowin, Julia

AU - Roeder, Claudia

AU - Bergman, Annika

AU - Schifflers, Mathias

PY - 2011/1/17

Y1 - 2011/1/17

N2 - BACKGROUND: To evaluate the cost burden of patients with advanced Parkinson's disease (PD) according to the waking hours per day spent in OFF state. An analysis of resource use comprising medical services, professional care and informal care data from an observational, cross-sectional study was conducted.METHODS: A total of 60 physicians comprising 40 neurologists and 20 geriatricians across the UK participating in the Adelphi PD Disease Specific Programme took part. There were 302 PD patients at H&Y stages 3-5. Patients were characterised according to the percentage of time per day spent in OFF state (<25%, 26-50%, 51-75%, >75%).RESULTS: Average 12-monthly total costs increased according to the time spent in OFF state from £25,630 in patients spending less than 25% of their waking hours in OFF to £62,147 for patients spending more than 75% of their time in OFF. Overall, 7% of costs were attributed to direct medical care, while 93% were split between direct non-medical professional care (50%) and indirect informal care (43%).LIMITATIONS: Low patient numbers in the more advanced disease stages of PD led to very little or no data to directly inform some of the severe health states of the analysis. Data gaps were filled in with data derived from a regression analysis which may affect the robustness of the analysis.CONCLUSION: This study illustrates the increasing costs of advancing PD, in particular related to the time spent in OFF state, and identifies that the foremost cost burden is associated with the care needs of the patient rather than medical services.

AB - BACKGROUND: To evaluate the cost burden of patients with advanced Parkinson's disease (PD) according to the waking hours per day spent in OFF state. An analysis of resource use comprising medical services, professional care and informal care data from an observational, cross-sectional study was conducted.METHODS: A total of 60 physicians comprising 40 neurologists and 20 geriatricians across the UK participating in the Adelphi PD Disease Specific Programme took part. There were 302 PD patients at H&Y stages 3-5. Patients were characterised according to the percentage of time per day spent in OFF state (<25%, 26-50%, 51-75%, >75%).RESULTS: Average 12-monthly total costs increased according to the time spent in OFF state from £25,630 in patients spending less than 25% of their waking hours in OFF to £62,147 for patients spending more than 75% of their time in OFF. Overall, 7% of costs were attributed to direct medical care, while 93% were split between direct non-medical professional care (50%) and indirect informal care (43%).LIMITATIONS: Low patient numbers in the more advanced disease stages of PD led to very little or no data to directly inform some of the severe health states of the analysis. Data gaps were filled in with data derived from a regression analysis which may affect the robustness of the analysis.CONCLUSION: This study illustrates the increasing costs of advancing PD, in particular related to the time spent in OFF state, and identifies that the foremost cost burden is associated with the care needs of the patient rather than medical services.

KW - Aged

KW - Cost of Illness

KW - Costs and Cost Analysis

KW - Cross-Sectional Studies

KW - Female

KW - Health Services/economics

KW - Humans

KW - Male

KW - Parkinson Disease/economics

KW - Severity of Illness Index

KW - United Kingdom

U2 - 10.3111/13696998.2010.551164

DO - 10.3111/13696998.2010.551164

M3 - Article

C2 - 21235405

VL - 14

SP - 130

EP - 139

JO - Journal of Medical Economics

JF - Journal of Medical Economics

SN - 1369-6998

IS - 1

ER -