The endothelium and its role in regulating vascular tone
Research output: Contribution to journal › Article › peer-review
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In: The open cardiovascular medicine journal, Vol. 4, 23.12.2010, p. 302-12.
Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - The endothelium and its role in regulating vascular tone
AU - Sandoo, Aamer
AU - van Zanten, Jet J C S Veldhuijzen
AU - Metsios, George S
AU - Carroll, Douglas
AU - Kitas, George D
PY - 2010/12/23
Y1 - 2010/12/23
N2 - The endothelium forms an important part of the vasculature and is involved in promoting an atheroprotective environment via the complementary actions of endothelial cell-derived vasoactive factors. Disruption of vascular homeostasis can lead to the development of endothelial dysfunction which in turn contributes to the early and late stages of atherosclerosis. In recent years an increasing number of non-invasive vascular tests have been developed to assess vascular structure and function in different clinical populations. The present review aims to provide an insight into the anatomy of the vasculature as well as the underlying endothelial cell physiology. In addition, an in-depth overview of the current methods used to assess vascular function and structure is provided as well as their link to certain clinical populations.
AB - The endothelium forms an important part of the vasculature and is involved in promoting an atheroprotective environment via the complementary actions of endothelial cell-derived vasoactive factors. Disruption of vascular homeostasis can lead to the development of endothelial dysfunction which in turn contributes to the early and late stages of atherosclerosis. In recent years an increasing number of non-invasive vascular tests have been developed to assess vascular structure and function in different clinical populations. The present review aims to provide an insight into the anatomy of the vasculature as well as the underlying endothelial cell physiology. In addition, an in-depth overview of the current methods used to assess vascular function and structure is provided as well as their link to certain clinical populations.
KW - Journal Article
U2 - 10.2174/1874192401004010302
DO - 10.2174/1874192401004010302
M3 - Article
C2 - 21339899
VL - 4
SP - 302
EP - 312
JO - The open cardiovascular medicine journal
JF - The open cardiovascular medicine journal
SN - 1874-1924
ER -