Standard Standard

The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomized controlled trial. / Orrell, Martin; Yates, Lauren; Leung, Phuong et al.
In: PLoS Medicine, 28.03.2017.

Research output: Contribution to journalArticlepeer-review

HarvardHarvard

Orrell, M, Yates, L, Leung, P, Kang, S, Hoare, Z, Whitaker, C, Burns, A, Knapp, M, Leroi, I, Moniz-Cook, E, Pearson, S, Simpson, S, Spector, A, Roberts, S, Russell, I, de Waal, H, Woods, R & Orgeta, V 2017, 'The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomized controlled trial', PLoS Medicine. https://doi.org/10.1371/journal.pmed.1002269

APA

Orrell, M., Yates, L., Leung, P., Kang, S., Hoare, Z., Whitaker, C., Burns, A., Knapp, M., Leroi, I., Moniz-Cook, E., Pearson, S., Simpson, S., Spector, A., Roberts, S., Russell, I., de Waal, H., Woods, R., & Orgeta, V. (2017). The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomized controlled trial. PLoS Medicine. https://doi.org/10.1371/journal.pmed.1002269

CBE

MLA

VancouverVancouver

Author

RIS

TY - JOUR

T1 - The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia

T2 - A randomized controlled trial

AU - Orrell, Martin

AU - Yates, Lauren

AU - Leung, Phuong

AU - Kang, Sujin

AU - Hoare, Zoe

AU - Whitaker, Christopher

AU - Burns, Alistair

AU - Knapp, Martin

AU - Leroi, Iracema

AU - Moniz-Cook, Esme

AU - Pearson, Stephen

AU - Simpson, Stephen

AU - Spector, Aimee

AU - Roberts, Stephen

AU - Russell, Ian

AU - de Waal, Hugo

AU - Woods, Robert

AU - Orgeta, Vasiliki

PY - 2017/3/28

Y1 - 2017/3/28

N2 - BackgroundCognitive Stimulation Therapy (CST) is a well-established group psychosocial intervention for people with dementia. There is evidence that homebased programmes of cognitive stimulation delivered by family caregivers maybenefit both the person and the caregiver. However, no previous studies haveevaluated caregiver-delivered CST. This study aimed to evaluate the effectiveness of a home-based, caregiver-led individual Cognitive Stimulation Therapy (iCST) program in (i) improving cognition and quality of life (QoL) for the person with dementia and (ii) mental and physical health (wellbeing) for the caregiver.Methods and FindingsA single-blind, pragmatic randomized trial (RCT) at eight study sites across the UK. The intervention and blinded assessment of outcomes were conducted inparticipants’ homes. 356 people with mild to moderate dementia and their caregivers recruited from memory services, and community mental health teams. Participants were randomly assigned to iCST (75, 30 minute sessions) or treatment as usual (TAU) control over 25 weeks. iCST sessions consisted of themed activities designed to be mentally stimulating and enjoyable. Caregivers delivering iCST received training and support from an unblind researcher.Primary outcomes were cognition (Alzheimer’s Disease Assessment Scale –cognitive [ADAS-Cog]) and self-reported quality of life (QoL) (Quality of LifeAlzheimer’s Disease [QoL-AD]) for the person with dementia, and general healthstatus (Short Form-12 [SF-12]) for the caregiver. Secondary outcomes included:quality of the caregiving relationship from the perspectives of the person and of the caregiver (Quality of the Carer Patient Relationships Scale), and health-related QoL (EQ5D) for the caregiver.

AB - BackgroundCognitive Stimulation Therapy (CST) is a well-established group psychosocial intervention for people with dementia. There is evidence that homebased programmes of cognitive stimulation delivered by family caregivers maybenefit both the person and the caregiver. However, no previous studies haveevaluated caregiver-delivered CST. This study aimed to evaluate the effectiveness of a home-based, caregiver-led individual Cognitive Stimulation Therapy (iCST) program in (i) improving cognition and quality of life (QoL) for the person with dementia and (ii) mental and physical health (wellbeing) for the caregiver.Methods and FindingsA single-blind, pragmatic randomized trial (RCT) at eight study sites across the UK. The intervention and blinded assessment of outcomes were conducted inparticipants’ homes. 356 people with mild to moderate dementia and their caregivers recruited from memory services, and community mental health teams. Participants were randomly assigned to iCST (75, 30 minute sessions) or treatment as usual (TAU) control over 25 weeks. iCST sessions consisted of themed activities designed to be mentally stimulating and enjoyable. Caregivers delivering iCST received training and support from an unblind researcher.Primary outcomes were cognition (Alzheimer’s Disease Assessment Scale –cognitive [ADAS-Cog]) and self-reported quality of life (QoL) (Quality of LifeAlzheimer’s Disease [QoL-AD]) for the person with dementia, and general healthstatus (Short Form-12 [SF-12]) for the caregiver. Secondary outcomes included:quality of the caregiving relationship from the perspectives of the person and of the caregiver (Quality of the Carer Patient Relationships Scale), and health-related QoL (EQ5D) for the caregiver.

U2 - 10.1371/journal.pmed.1002269

DO - 10.1371/journal.pmed.1002269

M3 - Article

JO - PLoS Medicine

JF - PLoS Medicine

SN - 1549-1676

ER -