The structural and functional diversification of the Toxicofera reptile venom system
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In: Toxicon, Vol. 60, No. 4, 15.09.2012, p. 434-448.
Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - The structural and functional diversification of the Toxicofera reptile venom system
AU - Wuster, W.
AU - Fry, B.G.
AU - Casewell, N.R.
AU - Wüster, W.
AU - Vidal, N.
AU - Young, B.
AU - Jackson, T.N.
PY - 2012/9/15
Y1 - 2012/9/15
N2 - The evolutionary origin and diversification of the reptilian venom system is described. The resolution of higher-order molecular phylogenetics has clearly established that a venom system is ancestral to snakes. The diversification of the venom system within lizards is discussed, as is the role of venom delivery in the behavioural ecology of these taxa (particularly Varanus komodoensis). The more extensive diversification of the venom system in snakes is summarised, including its loss in some clades. Finally, we discuss the contentious issue of a definition for “venom”, supporting an evolutionary definition that recognises the homology of both the venom delivery systems and the toxins themselves.
AB - The evolutionary origin and diversification of the reptilian venom system is described. The resolution of higher-order molecular phylogenetics has clearly established that a venom system is ancestral to snakes. The diversification of the venom system within lizards is discussed, as is the role of venom delivery in the behavioural ecology of these taxa (particularly Varanus komodoensis). The more extensive diversification of the venom system in snakes is summarised, including its loss in some clades. Finally, we discuss the contentious issue of a definition for “venom”, supporting an evolutionary definition that recognises the homology of both the venom delivery systems and the toxins themselves.
U2 - 10.1016/j.toxicon.2012.02.013
DO - 10.1016/j.toxicon.2012.02.013
M3 - Article
VL - 60
SP - 434
EP - 448
JO - Toxicon
JF - Toxicon
SN - 0041-0101
IS - 4
ER -