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Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients

Research output: Contribution to journal › Article › peer-review

Standard Standard

Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients. / Clayton, R.J.; Wilkinson, T.J.; OBrien, T.D. et al.
In: Rheumatology, Vol. 54, No. Suppl. 1, 28.04.2015, p. 78.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Clayton, RJ, Wilkinson, TJ, OBrien, TD, Lemmey, AB, Clayton, R, Wilkinson, T, Sheikh, F, Ahmad, Y, Whale, J, Jones, H, Chitale, S, Jones, J, Maddison, P & O'Brien, T 2015, 'Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients', Rheumatology, vol. 54, no. Suppl. 1, pp. 78.

APA

Clayton, R. J., Wilkinson, T. J., OBrien, T. D., Lemmey, A. B., Clayton, R., Wilkinson, T., Sheikh, F., Ahmad, Y., Whale, J., Jones, H., Chitale, S., Jones, J., Maddison, P., & O'Brien, T. (2015). Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients. Rheumatology, 54(Suppl. 1), 78.

CBE

Clayton RJ, Wilkinson TJ, OBrien TD, Lemmey AB, Clayton R, Wilkinson T, Sheikh F, Ahmad Y, Whale J, Jones H, et al. 2015. Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients. Rheumatology. 54(Suppl. 1):78.

MLA

Clayton, R.J. et al. "Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients". Rheumatology. 2015, 54(Suppl. 1). 78.

VancouverVancouver

Clayton RJ, Wilkinson TJ, OBrien TD, Lemmey AB, Clayton R, Wilkinson T et al. Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients. Rheumatology. 2015 Apr 28;54(Suppl. 1):78.

Author

Clayton, R.J. ; Wilkinson, T.J. ; OBrien, T.D. et al. / Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients. In: Rheumatology. 2015 ; Vol. 54, No. Suppl. 1. pp. 78.

RIS

TY - JOUR

T1 - Treat-to-Target Treatment Fails to Restore either Body Composition or Objectively Assessed Physical Function in Rheumatoid Arthritis Patients

AU - Clayton, R.J.

AU - Wilkinson, T.J.

AU - OBrien, T.D.

AU - Lemmey, A.B.

AU - Clayton, R.

AU - Wilkinson, T.

AU - Sheikh, F.

AU - Ahmad, Y.

AU - Whale, J.

AU - Jones, H.

AU - Chitale, S.

AU - Jones, J.

AU - Maddison, P.

AU - O'Brien, T.

PY - 2015/4/28

Y1 - 2015/4/28

N2 - Historically RA has been characterized by adverse changes in body composition (loss of muscle mass (MM) and excessive fat mass, especially trunk fat mass), termed rheumatoid cachexia. In turn, rheumatoid cachexia contributes to physical disability. Since rheumatoid cachexia is thought to be driven by inflammation, it would be anticipated that the success of treat-to-target (T2T) in reducing inflammation and disease activity would also benefit body composition and physical function. Pertinently, restoration of normal function is an explicit aim of EULAR and ACR recommendations and principles for T2T. This cross-sectional study evaluated the effect of T2T on body composition and objectively assessed function.

AB - Historically RA has been characterized by adverse changes in body composition (loss of muscle mass (MM) and excessive fat mass, especially trunk fat mass), termed rheumatoid cachexia. In turn, rheumatoid cachexia contributes to physical disability. Since rheumatoid cachexia is thought to be driven by inflammation, it would be anticipated that the success of treat-to-target (T2T) in reducing inflammation and disease activity would also benefit body composition and physical function. Pertinently, restoration of normal function is an explicit aim of EULAR and ACR recommendations and principles for T2T. This cross-sectional study evaluated the effect of T2T on body composition and objectively assessed function.

UR - http://rheumatology.oxfordjournals.org/content/54/suppl_1/i78.1.short

M3 - Article

VL - 54

SP - 78

JO - Rheumatology

JF - Rheumatology

SN - 1462-0324

IS - Suppl. 1

ER -