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Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes

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Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes. / Wade, Matthew J; Lo Jacomo, Anna; Armenise, Elena et al.
In: Journal of Hazardous Materials, Vol. 424, No. Pt B, 127456, 15.02.2022.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Wade, MJ, Lo Jacomo, A, Armenise, E, Brown, MR, Bunce, JT, Cameron, GJ, Fang, Z, Farkas, K, Gilpin, DF, Graham, DW, Grimsley, JMS, Hart, A, Hoffmann, T, Jackson, KJ, Jones, DL, Lilley, CJ, McGrath, JW, McKinley, JM, McSparron, C, Nejad, BF, Morvan, M, Quintela-Baluja, M, Roberts, AMI, Singer, AC, Souque, C, Speight, VL, Sweetapple, C, Walker, D, Watts, G, Weightman, A & Kasprzyk-Hordern, B 2022, 'Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes', Journal of Hazardous Materials, vol. 424, no. Pt B, 127456. https://doi.org/10.1016/j.jhazmat.2021.127456

APA

Wade, M. J., Lo Jacomo, A., Armenise, E., Brown, M. R., Bunce, J. T., Cameron, G. J., Fang, Z., Farkas, K., Gilpin, D. F., Graham, D. W., Grimsley, J. M. S., Hart, A., Hoffmann, T., Jackson, K. J., Jones, D. L., Lilley, C. J., McGrath, J. W., McKinley, J. M., McSparron, C., ... Kasprzyk-Hordern, B. (2022). Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes. Journal of Hazardous Materials, 424(Pt B), Article 127456. https://doi.org/10.1016/j.jhazmat.2021.127456

CBE

Wade MJ, Lo Jacomo A, Armenise E, Brown MR, Bunce JT, Cameron GJ, Fang Z, Farkas K, Gilpin DF, Graham DW, et al. 2022. Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes. Journal of Hazardous Materials. 424(Pt B):Article 127456. https://doi.org/10.1016/j.jhazmat.2021.127456

MLA

Wade, Matthew J et al. "Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes". Journal of Hazardous Materials. 2022. 424(Pt B). https://doi.org/10.1016/j.jhazmat.2021.127456

VancouverVancouver

Wade MJ, Lo Jacomo A, Armenise E, Brown MR, Bunce JT, Cameron GJ et al. Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes. Journal of Hazardous Materials. 2022 Feb 15;424(Pt B):127456. Epub 2021 Oct 8. doi: 10.1016/j.jhazmat.2021.127456

Author

Wade, Matthew J ; Lo Jacomo, Anna ; Armenise, Elena et al. / Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes. In: Journal of Hazardous Materials. 2022 ; Vol. 424, No. Pt B.

RIS

TY - JOUR

T1 - Understanding and managing uncertainty and variability for wastewater monitoring beyond the pandemic: Lessons learned from the United Kingdom national COVID-19 surveillance programmes

AU - Wade, Matthew J

AU - Lo Jacomo, Anna

AU - Armenise, Elena

AU - Brown, Mathew R

AU - Bunce, Joshua T

AU - Cameron, Graeme J

AU - Fang, Zhou

AU - Farkas, Kata

AU - Gilpin, Deidre F

AU - Graham, David W

AU - Grimsley, Jasmine M S

AU - Hart, Alwyn

AU - Hoffmann, Till

AU - Jackson, Katherine J

AU - Jones, David L

AU - Lilley, Chris J

AU - McGrath, John W

AU - McKinley, Jennifer M

AU - McSparron, Cormac

AU - Nejad, Behnam F

AU - Morvan, Mario

AU - Quintela-Baluja, Marcos

AU - Roberts, Adrian M I

AU - Singer, Andrew C

AU - Souque, Célia

AU - Speight, Vanessa L

AU - Sweetapple, Chris

AU - Walker, David

AU - Watts, Glenn

AU - Weightman, Andrew

AU - Kasprzyk-Hordern, Barbara

N1 - Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.

PY - 2022/2/15

Y1 - 2022/2/15

N2 - The COVID-19 pandemic has put unprecedented pressure on public health resources around the world. From adversity, opportunities have arisen to measure the state and dynamics of human disease at a scale not seen before. In the United Kingdom, the evidence that wastewater could be used to monitor the SARS-CoV-2 virus prompted the development of National wastewater surveillance programmes. The scale and pace of this work has proven to be unique in monitoring of virus dynamics at a national level, demonstrating the importance of wastewater-based epidemiology (WBE) for public health protection. Beyond COVID-19, it can provide additional value for monitoring and informing on a range of biological and chemical markers of human health. A discussion of measurement uncertainty associated with surveillance of wastewater, focusing on lessons-learned from the UK programmes monitoring COVID-19 is presented, showing that sources of uncertainty impacting measurement quality and interpretation of data for public health decision-making, are varied and complex. While some factors remain poorly understood, we present approaches taken by the UK programmes to manage and mitigate the more tractable sources of uncertainty. This work provides a platform to integrate uncertainty management into WBE activities as part of global One Health initiatives beyond the pandemic.

AB - The COVID-19 pandemic has put unprecedented pressure on public health resources around the world. From adversity, opportunities have arisen to measure the state and dynamics of human disease at a scale not seen before. In the United Kingdom, the evidence that wastewater could be used to monitor the SARS-CoV-2 virus prompted the development of National wastewater surveillance programmes. The scale and pace of this work has proven to be unique in monitoring of virus dynamics at a national level, demonstrating the importance of wastewater-based epidemiology (WBE) for public health protection. Beyond COVID-19, it can provide additional value for monitoring and informing on a range of biological and chemical markers of human health. A discussion of measurement uncertainty associated with surveillance of wastewater, focusing on lessons-learned from the UK programmes monitoring COVID-19 is presented, showing that sources of uncertainty impacting measurement quality and interpretation of data for public health decision-making, are varied and complex. While some factors remain poorly understood, we present approaches taken by the UK programmes to manage and mitigate the more tractable sources of uncertainty. This work provides a platform to integrate uncertainty management into WBE activities as part of global One Health initiatives beyond the pandemic.

U2 - 10.1016/j.jhazmat.2021.127456

DO - 10.1016/j.jhazmat.2021.127456

M3 - Article

C2 - 34655869

VL - 424

JO - Journal of Hazardous Materials

JF - Journal of Hazardous Materials

SN - 0304-3894

IS - Pt B

M1 - 127456

ER -