Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

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Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia. / Howe, Connor ; MacLeod, David ; Wainman, Liisa et al.
In: Chest, Vol. 158, No. 4, 01.10.2020, p. 1644-1650.

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Howe C, MacLeod D, Wainman L, Oliver S, Ainslie P. Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia. Chest. 2020 Oct 1;158(4):1644-1650. Epub 2020 Apr 25. doi: https://doi.org/10.1016/j.chest.2020.04.017

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Howe, Connor ; MacLeod, David ; Wainman, Liisa et al. / Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia. In: Chest. 2020 ; Vol. 158, No. 4. pp. 1644-1650.

RIS

TY - JOUR

T1 - Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia

AU - Howe, Connor

AU - MacLeod, David

AU - Wainman, Liisa

AU - Oliver, Sam

AU - Ainslie, Philip

PY - 2020/10/1

Y1 - 2020/10/1

N2 - Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.

AB - Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.

KW - exercise

KW - hypoxia

KW - noninvasive

KW - pulmonary gas exchange

KW - validation

U2 - https://doi.org/10.1016/j.chest.2020.04.017

DO - https://doi.org/10.1016/j.chest.2020.04.017

M3 - Article

VL - 158

SP - 1644

EP - 1650

JO - Chest

JF - Chest

SN - 0012-3692

IS - 4

ER -