Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia
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In: Chest, Vol. 158, No. 4, 01.10.2020, p. 1644-1650.
Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Validation of a Noninvasive Assessment of Pulmonary Gas Exchange During Exercise in Hypoxia
AU - Howe, Connor
AU - MacLeod, David
AU - Wainman, Liisa
AU - Oliver, Sam
AU - Ainslie, Philip
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.
AB - Pulmonary gas exchange efficiency, determined by the alveolar-to-arterial P o 2 difference (A-aD o 2), progressively worsens during exercise at sea-level; this response is further elevated during exercise in hypoxia. Traditionally, pulmonary gas exchange efficiency is assessed through measurements of ventilation and end-tidal gases paired with direct arterial blood gas (ABG) sampling. Because these measures have a number of caveats, particularly invasive blood sampling, the development of new approaches for the noninvasive assessment of pulmonary gas exchange is needed.
KW - exercise
KW - hypoxia
KW - noninvasive
KW - pulmonary gas exchange
KW - validation
U2 - 10.1016/j.chest.2020.04.017
DO - 10.1016/j.chest.2020.04.017
M3 - Article
VL - 158
SP - 1644
EP - 1650
JO - Chest
JF - Chest
SN - 0012-3692
IS - 4
ER -