TY - JOUR

T1 - Visuospatial transformation impairments in Parkinson's disease

AU - Kerai, Julie H

AU - Bracewell, R Martyn

AU - Hindle, John V

AU - Leek, E. Charles

PY - 2012

Y1 - 2012

N2 - Some previous studies have reported impairments in Parkinson's disease (PD) that affect performance on visuospatial tasks. The aim of this study was to further elucidate the underlying cognitive impairment to visuospatial processing in PD. Nondementing PD patients and neurologically normal, age-matched controls completed two tasks of visuospatial transformation. In Task 1, observers made perceptual matching judgments about the shape equivalence of two upright or rotated 2D novel patterns. Task 2 used a recognition memory paradigm in which participants first memorized a target object at a specific orientation and then made target/nontarget judgments to targets or visually similar distractors at varying orientations. Analyses of the regression slopes between response times and angular disparity showed that PD is associated with impairments affecting spatial transformation during image normalization in both tasks. The results also showed that the patients were more impaired, relative to controls, at spatial transformation during the perceptual matching of two images, than in the recognition memory task. It is suggested that PD can result in deficits affecting spatial transformation processes that are modulated by working memory and task demands.

AB - Some previous studies have reported impairments in Parkinson's disease (PD) that affect performance on visuospatial tasks. The aim of this study was to further elucidate the underlying cognitive impairment to visuospatial processing in PD. Nondementing PD patients and neurologically normal, age-matched controls completed two tasks of visuospatial transformation. In Task 1, observers made perceptual matching judgments about the shape equivalence of two upright or rotated 2D novel patterns. Task 2 used a recognition memory paradigm in which participants first memorized a target object at a specific orientation and then made target/nontarget judgments to targets or visually similar distractors at varying orientations. Analyses of the regression slopes between response times and angular disparity showed that PD is associated with impairments affecting spatial transformation during image normalization in both tasks. The results also showed that the patients were more impaired, relative to controls, at spatial transformation during the perceptual matching of two images, than in the recognition memory task. It is suggested that PD can result in deficits affecting spatial transformation processes that are modulated by working memory and task demands.

KW - Acoustic Stimulation

KW - Aged

KW - Disability Evaluation

KW - Female

KW - Humans

KW - Judgment

KW - Male

KW - Memory Disorders

KW - Middle Aged

KW - Neuropsychological Tests

KW - Parkinson Disease

KW - Perceptual Disorders

KW - Photic Stimulation

KW - Psychiatric Status Rating Scales

KW - Reaction Time

KW - Recognition (Psychology)

KW - Regression Analysis

KW - Space Perception

KW - Journal Article

U2 - 10.1080/13803395.2012.716396

DO - 10.1080/13803395.2012.716396

M3 - Article

C2 - 22943062

VL - 34

SP - 1053

EP - 1064

JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

SN - 1380-3395

IS - 10

ER -