C2-Symmetric Amino Acid Amide-Derived Organocatalysts
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Fersiynau electronig
Dolenni
- https://doi.org/10.3390/reactions5030027
Fersiwn derfynol wedi’i chyhoeddi
Trwydded: CC BY Dangos trwydded
N-alkylated C2-symmetric amino acid amide derivatives were shown to catalyse the Michael addition of 2-hydroxy-1,4-napthoquinone to β-nitrostyrene, achieving a maximum ee of 44%. The corresponding trifluoroacetic acid salts also catalysed the aldol reaction between 4-nitrobenzaldehyde and hydroxyacetone, leading to the formation of predominantly syn-aldol products in up to 55% ee. Aspects of the solvent dependence of the aldol reaction and the H-bonding of the catalyst were investigated.
| Iaith wreiddiol | Saesneg |
|---|---|
| Tudalennau (o-i) | 567-586 |
| Cyfnodolyn | Reactions |
| Cyfrol | 5 |
| Rhif y cyfnodolyn | 3 |
| Statws | Cyhoeddwyd - 24 Awst 2024 |