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COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type. / Nowparast Rostami, Hadiseh; Saville, Christopher; Klein, Christoph et al.
Yn: Biological Psychology, Cyfrol 127, Rhif July, 07.2017, t. 209-219.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

HarvardHarvard

Nowparast Rostami, H, Saville, C, Klein, C, Ouyang, G, Sommer, W, Zhou, C & Hildebrandt, A 2017, 'COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type.', Biological Psychology, cyfrol. 127, rhif July, tt. 209-219. https://doi.org/10.1016/j.biopsycho.2017.06.002

APA

Nowparast Rostami, H., Saville, C., Klein, C., Ouyang, G., Sommer, W., Zhou, C., & Hildebrandt, A. (2017). COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type. Biological Psychology, 127(July), 209-219. https://doi.org/10.1016/j.biopsycho.2017.06.002

CBE

Nowparast Rostami H, Saville C, Klein C, Ouyang G, Sommer W, Zhou C, Hildebrandt A. 2017. COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type. Biological Psychology. 127(July):209-219. https://doi.org/10.1016/j.biopsycho.2017.06.002

MLA

Nowparast Rostami, Hadiseh et al. "COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type.". Biological Psychology. 2017, 127(July). 209-219. https://doi.org/10.1016/j.biopsycho.2017.06.002

VancouverVancouver

Nowparast Rostami H, Saville C, Klein C, Ouyang G, Sommer W, Zhou C et al. COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type. Biological Psychology. 2017 Gor;127(July):209-219. Epub 2017 Meh 23. doi: 10.1016/j.biopsycho.2017.06.002

Author

Nowparast Rostami, Hadiseh ; Saville, Christopher ; Klein, Christoph et al. / COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type. Yn: Biological Psychology. 2017 ; Cyfrol 127, Rhif July. tt. 209-219.

RIS

TY - JOUR

T1 - COMT genotype is differentially associated with single trial variability of ERPs as a function of memory type.

AU - Nowparast Rostami, Hadiseh

AU - Saville, Christopher

AU - Klein, Christoph

AU - Ouyang, Guang

AU - Sommer, Werner

AU - Zhou, Changsong

AU - Hildebrandt, Andrea

PY - 2017/7

Y1 - 2017/7

N2 - Previous research on the association between intra-subject variability (ISV) in reaction times (RTs) and the Val158Met polymorphism of the catechol-o-methyltransferase gene (COMT; rs4680) has yielded mixed results. The present study compared the associations between COMT genotype and ISV in P3b latency measured during working and secondary memory tasks using residue iteration decomposition (RIDE) of single trial latencies. We compared the outcome of the present analyses with a previous analysis of the same data (N = 70, n-back tasks) using an alternative single-trial method. Additionally, we used RIDE to analyse the association between COMT genotype and ISV in an independent sample performing a different task (N = 91, face-recognition task). Analyses reconfirmed previous results from the n-back tasks, showing that Val alleles are associated with lower ISV. In the face recognition tasks, genotype interacted with task conditions, so Val homozygotes had higher ISV to unfamiliar faces than familiar ones but Met carriers showed no effect of familiarity. Moreover, in both datasets trial-by-trial RTs were predicted by P3b latencies. Therefore, the present data suggests that associations between COMT genotype and ISV depend on the type of cognitive processes, which may explain heterogeneity in previous results.

AB - Previous research on the association between intra-subject variability (ISV) in reaction times (RTs) and the Val158Met polymorphism of the catechol-o-methyltransferase gene (COMT; rs4680) has yielded mixed results. The present study compared the associations between COMT genotype and ISV in P3b latency measured during working and secondary memory tasks using residue iteration decomposition (RIDE) of single trial latencies. We compared the outcome of the present analyses with a previous analysis of the same data (N = 70, n-back tasks) using an alternative single-trial method. Additionally, we used RIDE to analyse the association between COMT genotype and ISV in an independent sample performing a different task (N = 91, face-recognition task). Analyses reconfirmed previous results from the n-back tasks, showing that Val alleles are associated with lower ISV. In the face recognition tasks, genotype interacted with task conditions, so Val homozygotes had higher ISV to unfamiliar faces than familiar ones but Met carriers showed no effect of familiarity. Moreover, in both datasets trial-by-trial RTs were predicted by P3b latencies. Therefore, the present data suggests that associations between COMT genotype and ISV depend on the type of cognitive processes, which may explain heterogeneity in previous results.

U2 - 10.1016/j.biopsycho.2017.06.002

DO - 10.1016/j.biopsycho.2017.06.002

M3 - Article

VL - 127

SP - 209

EP - 219

JO - Biological Psychology

JF - Biological Psychology

SN - 0301-0511

IS - July

ER -