Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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Yn: Neuroimage, Cyfrol 86, 01.02.2014, t. 43-52.
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
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T1 - Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA
AU - Mullins, Paul G
AU - McGonigle, David J
AU - O'Gorman, Ruth L
AU - Puts, Nicolaas A J
AU - Vidyasagar, Rishma
AU - Evans, C John
AU - Edden, Richard A E
AU - Cardiff Symposium on MRS of GABA
N1 - Copyright © 2012 Elsevier Inc. All rights reserved.
PY - 2014/2/1
Y1 - 2014/2/1
N2 - There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.
AB - There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.
KW - Algorithms
KW - Brain
KW - Humans
KW - Magnetic Resonance Spectroscopy
KW - Reproducibility of Results
KW - Sensitivity and Specificity
KW - gamma-Aminobutyric Acid
KW - Journal Article
KW - Research Support, N.I.H., Extramural
KW - Research Support, Non-U.S. Gov't
KW - Review
U2 - 10.1016/j.neuroimage.2012.12.004
DO - 10.1016/j.neuroimage.2012.12.004
M3 - Article
C2 - 23246994
VL - 86
SP - 43
EP - 52
JO - Neuroimage
JF - Neuroimage
SN - 1053-8119
ER -