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Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

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Standard Standard

Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA. / Mullins, Paul G; McGonigle, David J; O'Gorman, Ruth L et al.
In: Neuroimage, Vol. 86, 01.02.2014, p. 43-52.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Mullins, PG, McGonigle, DJ, O'Gorman, RL, Puts, NAJ, Vidyasagar, R, Evans, CJ, Edden, RAE & Cardiff Symposium on MRS of GABA 2014, 'Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA', Neuroimage, vol. 86, pp. 43-52. https://doi.org/10.1016/j.neuroimage.2012.12.004

APA

Mullins, P. G., McGonigle, D. J., O'Gorman, R. L., Puts, N. A. J., Vidyasagar, R., Evans, C. J., Edden, R. A. E., & Cardiff Symposium on MRS of GABA (2014). Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA. Neuroimage, 86, 43-52. https://doi.org/10.1016/j.neuroimage.2012.12.004

CBE

Mullins PG, McGonigle DJ, O'Gorman RL, Puts NAJ, Vidyasagar R, Evans CJ, Edden RAE, Cardiff Symposium on MRS of GABA. 2014. Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA. Neuroimage. 86:43-52. https://doi.org/10.1016/j.neuroimage.2012.12.004

MLA

Mullins, Paul G et al. "Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA". Neuroimage. 2014, 86. 43-52. https://doi.org/10.1016/j.neuroimage.2012.12.004

VancouverVancouver

Mullins PG, McGonigle DJ, O'Gorman RL, Puts NAJ, Vidyasagar R, Evans CJ et al. Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA. Neuroimage. 2014 Feb 1;86:43-52. Epub 2012 Dec 13. doi: 10.1016/j.neuroimage.2012.12.004

Author

Mullins, Paul G ; McGonigle, David J ; O'Gorman, Ruth L et al. / Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA. In: Neuroimage. 2014 ; Vol. 86. pp. 43-52.

RIS

TY - JOUR

T1 - Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA

AU - Mullins, Paul G

AU - McGonigle, David J

AU - O'Gorman, Ruth L

AU - Puts, Nicolaas A J

AU - Vidyasagar, Rishma

AU - Evans, C John

AU - Edden, Richard A E

AU - Cardiff Symposium on MRS of GABA

N1 - Copyright © 2012 Elsevier Inc. All rights reserved.

PY - 2014/2/1

Y1 - 2014/2/1

N2 - There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.

AB - There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.

KW - Algorithms

KW - Brain

KW - Humans

KW - Magnetic Resonance Spectroscopy

KW - Reproducibility of Results

KW - Sensitivity and Specificity

KW - gamma-Aminobutyric Acid

KW - Journal Article

KW - Research Support, N.I.H., Extramural

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1016/j.neuroimage.2012.12.004

DO - 10.1016/j.neuroimage.2012.12.004

M3 - Article

C2 - 23246994

VL - 86

SP - 43

EP - 52

JO - Neuroimage

JF - Neuroimage

SN - 1053-8119

ER -