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Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

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Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation. / Bedson, Emma; Bell, Diana; Carr, Daniel et al.
Yn: Health Technology Assessment, Cyfrol 18, Rhif 48, 07.2014, t. 1-159.

Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid

HarvardHarvard

Bedson, E, Bell, D, Carr, D, Carter, B, Hughes, D, Jorgensen, A, Lewis, H, Lloyd, K, McCaddon, A, Moat, S, Pink, J, Pirmohamed, M, Roberts, S, Russell, I, Sylvestre, Y, Tranter, R, Whitaker, R, Wilkinson, C & Williams, N 2014, 'Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation', Health Technology Assessment, cyfrol. 18, rhif 48, tt. 1-159. https://doi.org/10.3310/hta18480

APA

Bedson, E., Bell, D., Carr, D., Carter, B., Hughes, D., Jorgensen, A., Lewis, H., Lloyd, K., McCaddon, A., Moat, S., Pink, J., Pirmohamed, M., Roberts, S., Russell, I., Sylvestre, Y., Tranter, R., Whitaker, R., Wilkinson, C., & Williams, N. (2014). Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation. Health Technology Assessment, 18(48), 1-159. https://doi.org/10.3310/hta18480

CBE

Bedson E, Bell D, Carr D, Carter B, Hughes D, Jorgensen A, Lewis H, Lloyd K, McCaddon A, Moat S, et al. 2014. Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation. Health Technology Assessment. 18(48):1-159. https://doi.org/10.3310/hta18480

MLA

Bedson, Emma et al. "Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation". Health Technology Assessment. 2014, 18(48). 1-159. https://doi.org/10.3310/hta18480

VancouverVancouver

Bedson E, Bell D, Carr D, Carter B, Hughes D, Jorgensen A et al. Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation. Health Technology Assessment. 2014 Gor;18(48):1-159. doi: 10.3310/hta18480

Author

Bedson, Emma ; Bell, Diana ; Carr, Daniel et al. / Folate Augmentation of Treatment-Evaluation for Depression (FolATED) : randomised trial and economic evaluation. Yn: Health Technology Assessment. 2014 ; Cyfrol 18, Rhif 48. tt. 1-159.

RIS

TY - JOUR

T1 - Folate Augmentation of Treatment-Evaluation for Depression (FolATED)

T2 - randomised trial and economic evaluation

AU - Bedson, Emma

AU - Bell, Diana

AU - Carr, Daniel

AU - Carter, Ben

AU - Hughes, Dyfrig

AU - Jorgensen, Andrea

AU - Lewis, Helen

AU - Lloyd, Keith

AU - McCaddon, Andrew

AU - Moat, Stuart

AU - Pink, Joshua

AU - Pirmohamed, Munir

AU - Roberts, Seren

AU - Russell, Ian

AU - Sylvestre, Yvonne

AU - Tranter, Richard

AU - Whitaker, Rhiannon

AU - Wilkinson, Clare

AU - Williams, Nefyn

PY - 2014/7

Y1 - 2014/7

N2 - Abstract Background Folate deficiency is associated with depression. Despite the biological plausibility of a causal link, the evidence that adding folate enhances antidepressant treatment is weak. Objectives (1) Estimate the clinical effectiveness and cost-effectiveness of folic acid as adjunct to antidepressant medication (ADM). (2) Explore whether baseline folate and homocysteine predict response to treatment. (3) Investigate whether response to treatment depends on genetic polymorphisms related to folate metabolism.

AB - Abstract Background Folate deficiency is associated with depression. Despite the biological plausibility of a causal link, the evidence that adding folate enhances antidepressant treatment is weak. Objectives (1) Estimate the clinical effectiveness and cost-effectiveness of folic acid as adjunct to antidepressant medication (ADM). (2) Explore whether baseline folate and homocysteine predict response to treatment. (3) Investigate whether response to treatment depends on genetic polymorphisms related to folate metabolism.

KW - Adult

KW - Antidepressive Agents

KW - Cost-Benefit Analysis

KW - Depression

KW - Female

KW - Folic Acid

KW - Humans

KW - Male

KW - Polymorphism, Genetic

KW - Risk Factors

KW - Treatment Outcome

KW - Wales

KW - Journal Article

KW - Multicenter Study

KW - Randomized Controlled Trial

KW - Research Support, Non-U.S. Gov't

U2 - 10.3310/hta18480

DO - 10.3310/hta18480

M3 - Article

C2 - 25052890

VL - 18

SP - 1

EP - 159

JO - Health Technology Assessment

JF - Health Technology Assessment

SN - 1366-5278

IS - 48

ER -