Folate Augmentation of Treatment-Evaluation for Depression (FolATED): randomised trial and economic evaluation
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Fersiynau electronig
Dangosydd eitem ddigidol (DOI)
Abstract
Background
Folate deficiency is associated with depression. Despite the biological plausibility of a causal link, the evidence that adding folate enhances antidepressant treatment is weak.
Objectives
(1) Estimate the clinical effectiveness and cost-effectiveness of folic acid as adjunct to antidepressant medication (ADM). (2) Explore whether baseline folate and homocysteine predict response to treatment. (3) Investigate whether response to treatment depends on genetic polymorphisms related to folate metabolism.
Allweddeiriau
| Iaith wreiddiol | Saesneg |
|---|---|
| Tudalennau (o-i) | 1-159 |
| Cyfnodolyn | Health Technology Assessment |
| Cyfrol | 18 |
| Rhif y cyfnodolyn | 48 |
| Dynodwyr Gwrthrych Digidol (DOIs) | |
| Statws | Cyhoeddwyd - Gorff 2014 |