Real-time detection of DNA interactions with long-period fiber-grating-based biosensor

Allbwn ymchwil: Cyfraniad at gyfnodolynErthygladolygiad gan gymheiriaid

Fersiynau electronig

Dangosydd eitem ddigidol (DOI)

  • Xianfeng Chen
  • L. Zhang
  • K. Zhou
  • E. Davies
  • K. Sugden
  • I. Bennion
  • M. Hughes
  • A.V. Hine
Using an optical biosensor based on a dual-peak long-period fiber grating, we have demonstrated the detection of interactions between biomolecules in real time. Silanization of the grating surface was successfully realized for the covalent immobilization of probe DNA, which was subsequently hybridized with the complementary target DNA sequence. It is interesting to note that the DNA biosensor was reusable after being stripped off the hybridized target DNA from the grating surface, demonstrating a function of multiple usability.
Iaith wreiddiolSaesneg
Tudalennau (o-i)2541-2543
CyfnodolynOptics Letters
Cyfrol32
Rhif y cyfnodolyn17
Dynodwyr Gwrthrych Digidol (DOIs)
StatwsCyhoeddwyd - Medi 2007
Gweld graff cysylltiadau