1. Published

   Multiple imputation of multiple multi-item scales when a full imputation model is infeasible

   Hughes, D., Plumpton, C. O., Morris, T., Hughes, D. A. & White, I. R., 26 Jan 2016, In: BMC Research Notes. 9, 45, p. 1-15

   Research output: Contribution to journal › Article › peer-review

2. Published

   Improving Outcomes in Children and Young People with Cancer: Analysis of the Potential Economic Impact of the Guidance.

   Hughes, D., Linck, P., Tunnage, B., Hughes, D. A. & Edwards, R. T., 1 Jan 2005, 2005 ed. Unknown.

   Research output: Book/Report › Commissioned report

3. Published

   Current assessment of risk-benefit by regulators: is it time to introduce decision analyses?

   Hughes, D., Hughes, D. A., Bayoumi, A. M. & Pirmohamed, M., 1 Aug 2007, In: Clinical Pharmacology and Therapeutics. 82, 2, p. 123-127

   Research output: Contribution to journal › Article › peer-review

4. Published

   All Wales Medicines Strategy Group Final Appraisal Report - Icatibant (Firazyr) for symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults (with C1-esterase-inhibitor deficiency).

   Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

   Research output: Book/Report › Commissioned report

5. Published

   Eliciting patients' preferences using a discrete choice experiment questionnaire: the role played by qualitative data in questionnaire design

   Hughes, D., Longo, M., Hughes, D. A., Myles, S. & Lisles, C., 1 Mar 2006.

   Research output: Contribution to conference › Paper

6. Published

   All Wales Medicines Strategy Group Final Appraisal Report – Clofarabine (Evoltra)

   Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

   Research output: Book/Report › Commissioned report

7. Published

   The influence of non-compliance on the effectiveness and cost-effectiveness of drug therapies.

   Hughes, D. & Hughes, D. A., 1 Jan 2001, 2001 ed. Unknown.

   Research output: Book/Report › Commissioned report

8. Published

   Drugs for exceptionally rare diseases: do they deserve special status for funding?

   Hughes, D., Tunnage, B. & Yeo, S. T., 1 Nov 2005, In: QJM - An International Journal of Medicine. 98, 11, p. 829-836

   Research output: Contribution to journal › Article › peer-review

9. Published

   Adverse drug reactions in economic evaluations

   Hughes, D. & Hughes, D. A., 1 Jan 2007, In: Value in Health. 10, 3, p. A109

   Research output: Contribution to journal › Article › peer-review

10. Published

    Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity

    Hughes, D., Hughes, D. A., Vilar, F. J., Ward, C. C., Alfirevic, A., Park, B. K. & Pirmohamed, M., 1 Jun 2004, In: Pharmacogenetics. 14, 6, p. 335-342

    Research output: Contribution to journal › Article › peer-review

11. Published

    Methodological issues in the literature on costs of non-compliance in chronic diseases

    Hughes, D., Salas, M., Zuluaga, A., Hughes, D. A., Cowell, W., Lebmeie, M., Vardeva, K., Pisu, M. & Shinogle, J., 1 Nov 2008.

    Research output: Contribution to conference › Paper

12. Published

    Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses

    Hughes, D., Pink, J., Lane, S., Pirmohamed, M. & Hughes D.A., N. V., 31 Oct 2011, In: British Medical Journal. 343, p. 1-14

    Research output: Contribution to journal › Article › peer-review

13. Published

    Abacavir hypersensitivity: Is pre-prescription genotyping cost-effective?

    Hughes, D., Hughes, D. A. & Pirmohamed, M., 1 Nov 2003, In: Value in Health. 6, 6, p. 749

    Research output: Contribution to journal › Article › peer-review

14. Published

    Pharmacogenetic tests: the need for a level playing field

    Hughes, D., Pirmohamed, M. & Hughes, D. A., 1 Jan 2013, In: Nature Reviews Drug Discovery. 12, 3-4

    Research output: Contribution to journal › Article › peer-review

15. Published

    Drug compliance and pharmaceconomics

    Hughes, D. & Hughes, D. A., 1 Dec 2003.

    Research output: Contribution to conference › Paper

16. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Tenofovir disoproxil fumarate (Viread) for the treatment of hepatitis B.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

17. Published

    Economic evaluation during early (phase II) trials

    Hughes, D. & Hughes, D. A., 1 Nov 2002.

    Research output: Contribution to conference › Paper

18. Published

    All Wales Medicines Strategy Group Final Appraisal Report - Atazanavir (Reyataz) in treatment-experienced patients.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2008, 2008 ed. Unknown.

    Research output: Book/Report › Commissioned report

19. Published

    A parenting programme for children at risk of developing conduct disorder: A cost-effectiveness analysis

    Hughes, D., Edwards, R. T., Ceilleachair, A., Bywater, T., Hughes, D. A. & Hutchings, J., 1 May 2007.

    Research output: Contribution to conference › Paper

20. Published

    Economic evaluations during early (Phase II) drug development: A role for clinical trial simulations.

    Hughes, D., Hughes, D. A. & Walley, T., 1 Jan 2001, In: Pharmacoeconomics. 19, 11, p. 1069-1077

    Research output: Contribution to journal › Article › peer-review

21. Published

    A randomised controlled trial of the clinical effectiveness, safety and cost-effectiveness of adalimumab in combination with methotrexate for the treatment of juvenile idiopathic arthritis associated uveitis (SYCAMORE Trial)

    Hughes, D., Ramanan, A., Dick, A. D., Benton, D., Compeyrot-Lacassagne, S., Dawoud, D., Hardwick, B., Hickey, H., Hughes, D. A., Jones, A., Woo, P., Edelsten, C., Beresford, M. W. & The SYCAMORE Trail Management Group, N. V., 9 Jan 2014, In: Trials. 15, 14

    Research output: Contribution to journal › Article › peer-review

22. Published

    Abolition of prescription copayments in Wales: an observational study on dispensing rates.

    Hughes, D., Cohen, D., Alam, M. F., Dunstan, F. D., Myles, S., Hughes, D. A. & Routledge, P. A., 1 Aug 2010, In: Value in Health. 13, 5, p. 675-680

    Research output: Contribution to journal › Article › peer-review

23. Published

    Biosimilars: Evidential standards for health technology assessment.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

24. Published

    Effects of the abolition of prescription charges in Wales: A preliminary analysis

    Hughes, D., Hughes, D. A., Alam, F., Cohen, D., Dunstan, F. & Routledge, P., 1 Apr 2008.

    Research output: Contribution to conference › Paper

25. Published

    Impact of the abolition of the prescription charge in Wales

    Hughes, D. & Hughes, D. A., 1 Nov 2008.

    Research output: Contribution to conference › Paper

26. Published

    The economics of evergreening.

    Hughes, D. & Hughes, D. A., 1 Jan 2009.

    Research output: Contribution to conference › Paper

27. Published

    Methods for integrating medication compliance and persistence in pharmacoeconomic evaluations.

    Hughes, D., Hughes, D. A., Cowell, W., Koncz, T. & Cramer, J., 1 Nov 2007, In: Value in Health. 10, 6, p. 498-509

    Research output: Contribution to journal › Article › peer-review

28. Published

    All Wales Medicines Strategy Group Final Assessment Report – Agalsidase alfa (Replagal)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

29. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Dasatinib (Sprycel®) Chronic, accelerated or blast phase CML.

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

30. Published

    A prototype agent-based model of antimalarial drug compliance

    Hughes, D., McKean, J., Rahlf, S., Shorter, H., Barnish, G., Paton, R., McBurney, P., Hughes, D. A. & Hastings, I., 1 Aug 2007.

    Research output: Contribution to conference › Paper

31. Published

    Back to basics: what is the relationship between dose and duration of drug action?

    Hughes, D. & Hughes, D. A., 1 May 2006.

    Research output: Contribution to conference › Paper

32. Published

    All Wales Medicines Strategy Group Final Appraisal Report – Parathyroid hormone (Preotact)

    Hughes, D., Hughes, D. A. & All Wales Strategy Group., N. V., 1 Jan 2007, 2007 ed. Unknown.

    Research output: Book/Report › Commissioned report

33. Published

    Mechanism-Based Approach to the Economic Evaluation of Pharmaceuticals: Pharmacokinetic/Pharmacodynamic/Pharmacoeconomic Analysis of Rituximab for Follicular Lymphoma.

    Hughes, D., Pink, J., Lane, S. & Hughes, D. A., 19 Mar 2012, In: Pharmacoeconomics.

    Research output: Contribution to journal › Article › peer-review

34. Published

    What determines which interventions improve compliance, and do they improve health outcomes in a cost-effective manner?

    Hughes, D., Hughes, D. A., LaFleur.*, N. V., Salas, M. & Shinogle, J., 1 May 2007.

    Research output: Contribution to conference › Paper

35. Published

    Is exercise effective in promoting mental well-being in older age? A systematic review.

    Hughes, D., Linck, P. G., Windle, G., Hughes, D. A., Linck, P., Russell, I. T. & Woods, R. T., 1 Aug 2010, In: Aging and Mental Health. 14, 6, p. 652-669

    Research output: Contribution to journal › Article › peer-review

36. Published

    Cost–effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs

    Hughes, D., Verhof, T. I., Redekop, W. K., van Schie, R. M., Bayat, S., Daly, A. K., Geitona, M., Haschke-Becher, E., Hughes, D. A., Kamali, F., Levin, L. A., Manolopoulos, V. G., Pirmohamed, M., Siebert, U., Stingl, J. C., Wadelius, M., de Boer, A. & Maitland-van der Zee, A. H., 1 Sept 2012, In: Pharmacogenomics. 13, 12, p. 1405-1417

    Research output: Contribution to journal › Article › peer-review

37. Published

    The problem of orphan drugs

    Hughes, D., Ferner, R. E. & Hughes, D. A., 16 Nov 2010, In: British Medical Journal. 341, p. 335-341

    Research output: Contribution to journal › Article › peer-review

38. Published

    Rare disease prevention and treatment: The need for a level playing field

    Hughes, D. & Plumpton, C., Feb 2018, In: Pharmacogenomics. 19, 3, p. 243-247

    Research output: Contribution to journal › Article › peer-review

39. Published

    Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control Study

    Hughes, D. & Poletti-Hughes, J., 21 Oct 2016, In: PLoS ONE. 11, 10, e0164681.

    Research output: Contribution to journal › Article › peer-review

40. Published

    Economics of pharmacogenetic guided treatments: Underwhelming or overstated?

    Hughes, D., May 2018, In: Clinical Pharmacology and Therapeutics. 103, 5, p. 749-751

    Research output: Contribution to journal › Article › peer-review

41. Published

    Does legislation to prevent alcohol sales to drunk individuals work? Measuring the propensity for night-time sales to drunks in a UK city

    Hughes, K., Bellis, M. A., Leckenby, N., Quigg, Z., Hardcastle, K., Sharples, O. & Llewellyn, D. J., 15 Jan 2014, In: Journal of Epidemiology and Community Health. 68, p. 453-456

    Research output: Contribution to journal › Article › peer-review

42. Published

    Global development and diffusion of outcome evaluation research for interpersonal and self-directed violence prevention from 2007 to 2013: A systematic review

    Hughes, K., Bellis, M. A., Hardcastle, K. A., Butchart, A., Dahlberg, L. L., Mercy, J. A. & Mikton, C., 5 Oct 2014, In: Aggression and Violent Behavior. 19, 6, p. 655-662

    Research output: Contribution to journal › Article › peer-review

43. Published

    Associations between e-cigarette access and smoking and drinking behaviours in teenagers

    Hughes, K., Bellis, M. A., Hardcastle, K. A., McHale, P., Bennett, A., Ireland, R. & Pike, K., 31 Mar 2015, In: BMC Public Health. 15, 244

    Research output: Contribution to journal › Article › peer-review

44. Published

    Substance use, violence, and unintentional injury in young holidaymakers visiting Mediterranean destinations

    Hughes, K., Bellis, M. A., Calafat, A., Blay, N., Kokkevi, A., Boyiadji, G., Mendes, M. D. R. & Bajcàrova, L., 4 Mar 2011, In: Journal of Travel Medicine. 18, 2, p. 80-9 10 p.

    Research output: Contribution to journal › Article › peer-review

45. Published

    Drunk and disorganised: relationships between bar characteristics and customer intoxication in European drinking environments

    Hughes, K., Quigg, Z., Bellis, M. A., Calafat, A., van Hasselt, N., Kosir, M., Voorham, L., Goossens, F. X., Duch, M. & Juan, M., 12 Nov 2012, In: International Journal of Environmental Research and Public Health. 9, 11, p. 4068-82 15 p.

    Research output: Contribution to journal › Article › peer-review

46. Published

    Sexual behaviour among casual workers in an international nightlife resort: a case control study

    Hughes, K. & Bellis, M. A., 21 Feb 2006, In: BMC Public Health. 6, p. 39

    Research output: Contribution to journal › Article › peer-review

47. Published

    Child injury: using national emergency department monitoring systems to identify temporal and demographic risk factors

    Hughes, K., McHale, P., Wyke, S., Lowey, H. & Bellis, M. A., Apr 2014, In: Injury Prevention. 20, 2, p. 74-80 7 p.

    Research output: Contribution to journal › Article › peer-review

48. Published

    Drinking behaviours and blood alcohol concentration in four European drinking environments: a cross-sectional study

    Hughes, K., Quigg, Z., Bellis, M. A., van Hasselt, N., Calafat, A., Kosir, M., Juan, M., Duch, M. & Voorham, L., 12 Dec 2011, In: BMC Public Health. 11, p. 918

    Research output: Contribution to journal › Article › peer-review

49. Published

    Relationships between adverse childhood experiences and adult mental well-being: results from an English national household survey

    Hughes, K., Lowey, H., Quigg, Z. & Bellis, M. A., 3 Mar 2016, In: BMC Public Health. 16, p. 222

    Research output: Contribution to journal › Article › peer-review

50. Published

    Alcohol, nightlife and violence: the relative contributions of drinking before and during nights out to negative health and criminal justice outcomes

    Hughes, K., Anderson, Z., Morleo, M. & Bellis, M. A., Jan 2008, In: Addiction. 103, 1, p. 60-5 6 p.

    Research output: Contribution to journal › Article › peer-review