Professor Dyfrig Hughes
Athro mewn Ffarmacoeconomeg / Cyfarwyddwr Ymchwil
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A Systematic Review of Patient Preferences for Subcutaneous Medications
Ridyard, C., Dawoud, D. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
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Development of a Database of Instruments for Resource-Use Measurement: Purpose, Feasibility, and Design
DIRUM Team, 1 Jul 2012, In: Value in Health. 15, 5, p. 650-655Research output: Contribution to journal › Article › peer-review
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Cost-effectiveness of paediatric central venous catheters in the UK: A secondary publication from the CATCH clinical trial
Ridyard, C., Plumpton, C., Gilbert, R. E. & Hughes, D., 19 Sept 2017, In: Frontiers in Pharmacology. 8, 644.Research output: Contribution to journal › Article › peer-review
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Pump-Downloaded Insulin Usage For The First 12 Months In A Cohort of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., Nov 2017, In: Value in Health. 20, 9, p. A481 - A482Research output: Contribution to journal › Article › peer-review
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Review of the use of resource use instruments based on patient recall in relation to other methods of resource use estimation
Ridyard, C. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
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Methods for the collection of resource use data within clinical trials: A systematic review of studies funded by the UK Health Technology Assessment Program
Ridyard, C. H. & Hughes, D., 1 Dec 2010, In: Value in Health. 13, 8, p. 867-872Research output: Contribution to journal › Article › peer-review
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Review of resource-use measures in UK economic evaluations
Ridyard, C. & Hughes, D., 2015, PSSRU Unit Costs of Health and Social Care 2015 . Curtis, L. & Burns, A. (eds.). University of Kent, Canterbury, p. 22-31 10 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Taxonomy for methods of resource use measurement
DIRUM Team, 23 Jan 2015, In: Health Economics. 24, 3, p. 372-378Research output: Contribution to journal › Letter › peer-review
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Continuous Subcutaneous Infusion Versus Multiple Dose Injection of Insulin For Newly-Diagnosed T1D Paediatric Patients: A Cost-Utility Analysis
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A582Research output: Contribution to journal › Article › peer-review
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Review of the Use of Resource Use Instruments Based on Patient Recall in Relation to Other Methods of Cost Estimation
Ridyard, C. & Hughes, D., Nov 2013.Research output: Contribution to conference › Paper › peer-review
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Use Of The Ims Core Diabetes Model (CDM) In A Long-Term Projected Health Economic Comparison Of CSII And MDI Treatments Of Type 1 Diabetes (T1D) In A Newly-Diagnosed Population Of Paediatric Patients
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A580Research output: Contribution to journal › Article › peer-review
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Patterns In Working Days Lost By Parents Of Children Newly-Diagnosed With Type 1 Diabetes (T1D)
Ridyard, C., Blair, J. & Hughes, D., 20 Oct 2017, In: Value in Health. 20, 9, p. A590Research output: Contribution to journal › Article › peer-review
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Patient-level information and costing systems (PLICS) as a source of routinely collected cost data for trial-based economic evaluations
Ridyard, C. & Hughes, D., 7 May 2017, p. P141. 1 p.Research output: Contribution to conference › Poster › peer-review
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A systematic review of patients' perspectives on the subcutaneous route of medication administration
Ridyard, C., Dawoud, D. M., Tuersley, L. V. & Hughes, D., Aug 2016, In: Patient: Patient–Centered Outcomes Research. 9, 4, p. 281-292Research output: Contribution to journal › Article › peer-review
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What really matters? A mixed methods study of treatment preferences and priorities among people with epilepsy in the UK
Ring, A., Jacoby, A., Baker, G., Holmes, E., Hughes, D., Kierans, C. & Marson, A., Jun 2019, In: Epilepsy and Behavior. 95, p. 181-191Research output: Contribution to journal › Article › peer-review
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Enhancing methodical approaches for studying bilingualism in healthcare communication: report of a trial feasibility study.
Roberts, G. W., Hughes, D., Roberts, G., Owen, H., Hughes, L., Whitaker, R., Deuchar, M., Hughes, D. A., Llewelyn, S., John, S., Irvine, F., Owen, B. & Rowlands, A., 1 Jan 2010.Research output: Contribution to conference › Paper
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Folate Augmentation of Treatment – Evaluation for Depression (FolATED): protocol of a randomised controlled trial.
Russell, I. T., Slegg, G. P., Roberts, S. H., Bedson, E., Hughes, D., Lloyd, K., Moat, S., Pirmohamed, M., Slegg, G., Tranter, R., Whitaker, R., Wilkinson, C. & Russell, I., 15 Nov 2007, In: BMC Psychiatry. 7, 1, p. 65Research output: Contribution to journal › Article › peer-review
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Supply-side cost-effectiveness thresholds: questions for evidence-based policy
Sampson, C., Zamora, B., Watson, S., Cairns, J., Chalkidou, K., Cubi-Molla, P., Devlin, N., García-Lorenzo, B., Hughes, D., Leech, A. & Towse, A., Sept 2022, In: Applied Health Economics and Health Policy. 20, 5, p. 651-667Research output: Contribution to journal › Article › peer-review
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Opportunity costs and local health service spending decisions: a qualitative study from Wales
Schaffer, S. K., Sussex, J., Hughes, D. & Devlin, N., 25 Mar 2016, In: BMC Health Services Research. 16, 103Research output: Contribution to journal › Article › peer-review
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Population pharmacokinetic and pharmacodynamic modelling of the antimalarial chemotherapy chlorproguanil/dapsone.
Simpson, J. A., Hughes, D., Manyando, C., Bojang, K., Aarons, L., Winstanley, P., Edwards, G., Watkins, W. A. & Ward, S., 1 Mar 2006, In: British Journal of Clinical Pharmacology. 61, 3, p. 289-300Research output: Contribution to journal › Article › peer-review
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Clinical interventions to improve adherence to urate-lowering therapy in patients with gout: a systematic review
Sinnappah, K. A., Stocker, S. L., Chan, J. S., Hughes, D. A. & Wright, D. F. B., 25 Jun 2022, In: International Journal of Pharmacy Practice. 30, 3, p. 215-225 11 p.Research output: Contribution to journal › Article › peer-review
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A framework for understanding sources of bias in medication adherence research
Sinnappah, K. A., Hughes, D., Stocker, S. L., Vrijens, B., Aronson, J. K. & Wright, D. F. B., Nov 2023, In: British Journal of Clinical Pharmacology. 89, 11, p. 3444-3453Research output: Contribution to journal › Article › peer-review
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Cost and clinical consequence of antibiotic non-adherence in acute exacerbations of chronic bronchitis.
Sorensen, S. V., Baker, T., Fleurence, R., Dixon, J., Roberts, C., Haider, S. & Hughes, D., 1 Aug 2009, In: International Journal of Tuberculosis and Lung Disease. 13, 8, p. 945-954Research output: Contribution to journal › Article › peer-review
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What is the effectiveness and cost-effectiveness of interventions in reducing the harms for children and young people who have been exposed to domestic violence or abuse: a rapid review.
Spencer, L., Hendry, A., Makanjuola, A., Pisavadia, K., Davies, J., Albustami, M., Anthony, B., Wilkinson, C., Fitzsimmons, D., Hughes, D., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 10 May 2023, 79 p.Research output: Book/Report › Commissioned report
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The costs and cost-effectiveness of different service models of palliatice care, focusing on end of life care: A rapid review
Spencer, L., Anthony, B., Davies, J., Pisavadia, K., Gillen, E., Noyes, J., Fitzsimmons, D., Lewis, R., Cooper, A., Hughes, D., Edwards, R. T. & Edwards, A., 7 Mar 2024, MedRxiv, 118 p.Research output: Working paper › Preprint
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RES00038. Wales COVID-19 Evidence Centre. A rapid evidence summary of the cost impact of Long COVID on employment and caring responsibilities
Spencer, L., Hendry, A., Davies, J., Pisavadia, K., Hughes, D. & Edwards, R. T., May 2022, Welsh Government. 18 p.Research output: Book/Report › Other report
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What interventions or best practice are there to support people with Long COVID, or similar post-viral conditions or conditions characterised by fatigue, to return to normal activities: a rapid review
Spencer, L., Hendry, A., Makanjuola, A., Anthony, B., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 28 Jan 2023, 34 p. (MedRxiv).Research output: Working paper › Preprint
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Have infection control and prevention measures resulted in any adverse outcomes for care home and domiciliary care residents and staff? Report number: RR_00018 (November 2021)
Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 1 Nov 2021, 36 p.Research output: Book/Report › Other report › peer-review
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What is the long-term impact of COVID-19 on the Health-Related Quality of Life of individuals with mild symptoms (or non-hospitalised): A rapid review
Spencer, L., Hendry, A., Makanjuola, A., Davies, J., Pisavadia, K., Hughes, D., Fitzsimmons, D., Wilkinson, C., Edwards, R. T., Lewis, R., Cooper, A. & Edwards, A., 9 Sept 2022, Health and Care Research Wales, 47 p.Research output: Working paper › Preprint
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What innovations can address inequalities experienced by women and girls due to the COVID-19 pandemic across the different areas of life/domains: work, health, living standards, personal security, participation and education? Report number – RR00027 (January 2022). Gender Inequalities: COVID-19 initiatives
Spencer, L., Hartfiel, N., Hendry, A., Anthony, B., Makanjuola, A., Pisavadia, K., Davies, J., Bray, N., Hughes, D., Wilkinson, C., Fitzsimmons, D. & Edwards, R. T., 15 Jan 2022, Health and Care Research Wales.Research output: Book/Report › Commissioned report › peer-review
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RES00019. Wales COVID-19 Evidence Centre. A rapid evidence summary indicating the evidence of the inverse care law in social care in Wales and has this been exacerbated by the COVID-19 pandemic?
Spencer, L., Hendry, A., Makanjuola, A., Hughes, D., Wilkinson, C., Pisavadia, K., Davies, J., Fitzsimmons, D. & Edwards, R. T., Feb 2022, Welsh Government. 33 p.Research output: Book/Report › Other report
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Value of improving patient safety: Health-economic considerations for Rapid Response Systems – a Rapid Review of the Literature and Expert Round Table
Subbe, C., Hughes, D., Lewis, S., Holmes, E., Kalkman, C. J., So, R. K., Tranka, S. & Welch, J., 17 Apr 2023, In: BMJ Open. 13, 4, e065819.Research output: Contribution to journal › Article › peer-review
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Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care
Swift, B., Jain, L., White, C., Chandrasekaran, V., Bhandari, A., Hughes, D. & Jadhav, P., Sept 2018, In: Clinical and Translational Science. 11, 5, p. 450-460 11 p.Research output: Contribution to journal › Article › peer-review
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Core items for a standardized resource-use measure (ISRUM): expert Delphi consensus survey
Thom, J., Brookes, S. T., Ridyard, C., Riley, R., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., Jun 2018, In: Value in Health. 21, 6, p. 640-649Research output: Contribution to journal › Article › peer-review
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Core items for a standardised resource-use measure (ISRUM):expert Delphi consensus survey
Thorn, J., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S., Thornton, G. & Hollingworth, W., 7 May 2017, p. P265. 1 p.Research output: Contribution to conference › Poster › peer-review
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Health economics analysis plans: the current state of play
Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 7 May 2017, p. P144. 1 p.Research output: Contribution to conference › Poster › peer-review
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Content of Health Economics Analysis Plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
Thorn, J., Davies, C. F., Brookes, S., Noble, S., Dritsaki, M., Gray, E., Hughes, D., Mihaylova, B., Petrou, S., Ridyard, C., Sach, T., Wilson, E., Wordsworth, S. & Hollingworth, W., 1 Apr 2021, In: Value in Health. 24, 4, p. 539-547 9 p.Research output: Contribution to journal › Article › peer-review
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Identification Of Items For A Standardised Resource-Use Measure: Review Of Current Instruments
Thorn, J. C., Ridyard, C., Riley, R., Brookes, S., Hughes, D., Wordsworth, S., Noble, S. & Hollingworth, W., Nov 2015.Research output: Contribution to conference › Paper › peer-review
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Resource-Use Measurement Based on Patient Recall: Issues and Challenges for Economic Evaluation
Thorn, J. C., Coast, J., Cohen, D., Hollingworth, W., Knapp, M., Noble, S. M., Ridyard, C. H., Wordsworth, S. & Hughes, D., 1 Jun 2013, In: Applied Health Economics and Health Policy. 11, 3, p. 155-161Research output: Contribution to journal › Article › peer-review
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Health Economics Analysis Plans: Where Are We Now?
Thorn, J., Ridyard, C., Hughes, D., Wordsworth, S., Mihaylova, B., Noble, S. & Hollingworth, W., 3 Nov 2016, p. A397. 1 p.Research output: Contribution to conference › Poster › peer-review
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Utilising Benefit-Risk Assessments within Clinical Trials – A Protocol for the BRAINS project
Totton, N., Julious, S., Hughes, D., Cook, J., Biggs, K., Coates, L., Cook, A., Hewitt, C. & Day, S., 19 Jan 2021, In: Trials. 22, 68.Research output: Contribution to journal › Article › peer-review
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A proposal for using benefit-risk methods to improve the prominence of adverse event results when reporting trials
Totton, N., Waddingham, E., Owen, R., Julious, S., Hughes, D. & Cook, J., 22 Jun 2024, In: Trials. 25, 409.Research output: Contribution to journal › Article › peer-review
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Appropriate design and reporting of superiority, equivalence and non-inferiority clinical trials incorporating a benefit risk assessment: the BRAINS study including expert workshop
Totton, N., Julious, S., Coates, E., Hughes, D., Cook, J., Biggs, K., Hewitt, C., Day, S. & Cooke, A., Oct 2023, In: Health Technology Assessment. 27, 20, 86 p.Research output: Contribution to journal › Article › peer-review
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Acceptability of generic versus innovator oral medicines: not only a matter of taste
Tuleu, C., Hughes, D., Clapham, D., Vallet, T. & Ruiz, F., Feb 2021, In: Drug Discovery Today. 26, 2, p. 329-343Research output: Contribution to journal › Article › peer-review
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New Medicines in Wales: The All Wales Medicines Strategy Group (AWMSG) Appraisal Process and Outcomes
Varnava, A., Samuels, K., Hughes, D. & Routledge, P. A., May 2018, In: Pharmacoeconomics. 36, 5, p. 613-624 12 p.Research output: Contribution to journal › Article › peer-review
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Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden
Verhoef, T. I., Redekop, W. K., Langenskiold, S., Kamali, F., Wadelius, M., Burnside, G., Maitland-van der Zee, A. H., Hughes, D. & Pirmohamed, M., Oct 2016, In: The Pharmacogenomics Journal. 16, p. 478–484Research output: Contribution to journal › Article › peer-review
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Trends and influences on use of antidiabetic drugs in England, 1992-2003.
Walley, T., Hughes, D. & Kendall, H., 1 Nov 2005, In: Pharmacoepidemiology and Drug Safety. 14, 11, p. 769-773Research output: Contribution to journal › Article › peer-review
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Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT
Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Bostock, J., Hay, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson, P. J., Hughes, D., Marson, A. & Williamson, P. R., Apr 2021, In: Health Technology Assessment. 25, 24, 86 p.Research output: Contribution to journal › Article › peer-review
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Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controlled trial and economic evaluation
Wilby, M. J., Best, A., Wood, E., Burnside, G., Bedson, E., Short, H., Wheatley, D., Hill-McManus, D., Sharma, M., Clark, S., Baranidharan, G., Price, C., Mannion, R., Hutchinson , P. J., Hughes, D., Marson, A. G. & Williamson, P., 1 May 2021, In: The Lancet Rheumatology. 3, 5, p. e347-e356Research output: Contribution to journal › Article › peer-review
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Carer-administration of as-needed sub-cutaneous medication for breakthrough symptoms in homebased dying patients: a UK study (CARIAD)
Wilkinson, C., Poolman, M., Roberts, J., Wee, B., Hiscock, J., Hughes, D., Nelson, A., Perkins, P., Johnstone, R. P., Reymond, E., Foster, B., O'Connor, J., Jones, S., Hoare, Z., Roberts, R., Byrne, A., Healy, S. & Lewis, P., 1 Sept 2017.Research output: Contribution to conference › Poster › peer-review