Dr Edgar Hartsuiker

Senior Lecturer in Biomedical Sciences (Cancer Biology)

  1. 2023
  2. Published

    Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade

    Alblihy, A., Ali, R., Algethami, M., Ritchie, A. A., Shoqafi, A., Alqahtani, S., Mesquita, K. A., Toss, M. S., Ordóñez-Morán, P., Jeyapalan, J. N., Dekker, L., Salerno, M., Hartsuiker, E., Grabowska, A. M., Rakha, E. A., Mongan, N. P. & Madhusudan, S., 30 Jun 2023, In: International journal of molecular sciences. 24, 13

    Research output: Contribution to journalArticlepeer-review

  3. 2020
  4. Published

    Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication

    Böckemeier, L., Kraehenbuehl, R., Keszthelyi, A., Gasasira, M. U., Vernon, E., Beardmore, R., Broberg Vågbø, C., Chaplin, D., Collins, S., Krokan, H. E., Lambert, S. A. E., Paisz, B. & Hartsuiker, E., 29 May 2020, In: Science Advances. 6, 22, 9 p., eaaz4126.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Data presenting the synthesis of three novel stimuli responsive hyperbranched polymers synthesised via RAFT polymerisation and the bio conjugation of folic acid

    Blackburn, C., Tai, H., Salerno, M., Wang, X., Senan, C., Ratcliffe, I., Hartsuiker, E. & Wang, W., Feb 2020, In: Data in Brief. 28, 104861.

    Research output: Contribution to journalArticlepeer-review

  6. 2019
  7. Published

    Folic acid and rhodamine labelled pH responsive hyperbranched polymers: Synthesis, characterization and cell uptake studies

    Blackburn, C., Tai, H., Salerno, M., Wang, X., Hartsuiker, E. & Wang, W., Nov 2019, In: European Polymer Journal. 120, 109259.

    Research output: Contribution to journalArticlepeer-review

  8. 2018
  9. Published

    Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast.

    Roguev, A., Ryan, C. J., Xu, J., Colson, I., Hartsuiker, E. & Krogan, N., Feb 2018, In: Cold Spring Harbor Protocols. 2018, 2

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Genetic Interaction Screens in Schizosaccharomyces pombe Using the Pombe Epistasis Mapper (PEM) System and a Manual Colony Replicator.

    Colson, I. & Hartsuiker, E., Feb 2018, In: Cold Spring Harbor Protocols. 2018, 2

    Research output: Contribution to journalArticlepeer-review

  11. Published

    High-Throughput Quantitative Genetic Interaction Mapping in the Fission Yeast Schizosaccharomyces pombe.

    Roguev, A., Ryan, C. J., Hartsuiker, E. & Krogan, N. J., Feb 2018, In: Cold Spring Harbor Protocols. 2018, 2, p. 75-81 7 p.

    Research output: Contribution to journalArticlepeer-review

  12. 2017
  13. Published

    Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication

    Fleck, O., Fahnøe, U., Løvschal, K. V., Gasasira Uwamahoro, M-F., Marinova, I. N., Kragelund, B. B., Carr, A. M., Hartsuiker, E., Holmberg, C. & Nielsen, O., 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.

    Research output: Contribution to journalArticlepeer-review

  14. 2015
  15. Published

    The DNA-Binding Domain of S-pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers

    Zech, J., Godfrey, E. L., Masai, H., Hartsuiker, E. & Dalgaard, J. Z., 22 Jul 2015, In: PLoS ONE. 10, 7

    Research output: Contribution to journalArticlepeer-review

  16. Published

    UV induced ubiquitination of the yeast Rad4-Rad23 complex promotes survival by regulating cellular dNTP pools

    Zhou, Z., Humphryes, N., van Eijk, P., Waters, R., Yu, S. R., Kraehenbuehl, R., Hartsuiker, E. & Reed, S. H., 6 Jul 2015, In: Nucleic Acids Research. 43, 15, p. 7360-7370

    Research output: Contribution to journalArticlepeer-review

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