Research Portal

Dr Paddy Murphy

Honorary Professor

Affiliations

ORCID: 0000-0002-0790-0242

Contact info

Dr Patrick J. Murphy

School of Natrual Sciences 

Alun Roberts Building

Bangor

LL57 2UW

Tel: 01248 382375

Email:  chs027@bangor.ac.uk

1 - 50 out of 104Page size: 50
  1. Published

    Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal

    Whiteland, H., Crusco, A., Bloemberg, L. W., Tibble-Howlings, J., Forde-Thomas, J., Coghlan, A., Murphy, P. J. & Hoffmann, K. F., 19 Oct 2020, In: PLoS Neglected Tropical Diseases. 14, 10, p. e0008630

    Research output: Contribution to journal › Article › peer-review

  2. Published

    Synthesis and biological activity of analogues of batzelladine F

    Vale, S. A., Bennett, E. L., Black, G. P., Brown, P., Hizi, A., Jaffar, M., Leyland, J. P., Martin, C., Oz-Gleenberg, I., Murphy, P. J., Roberts, T. D. & Thornhill, A. J., 6 Feb 2013, In: Tetrahedron. 69, 14, p. 3061-3066

    Research output: Contribution to journal › Article › peer-review

  3. Published

    Triacylglycerol composition of British bluebell (Hyacinthoides non-scripta) seed oil

    Thoss, V., Murphy, P. J., Marriott, R. & Wilson, T., 10 Apr 2012, In: RSC Advances. 12, 2, p. 5314-5322

    Research output: Contribution to journal › Article › peer-review

  4. Published

    Synthetic marine guanidines are effective antileishmanial compounds by altering the plasma membrane permeability

    Tempone, A. G., Martins, L. F., Pinto, E. G., Mesquita, J. T., Bennett, E. L., Black, G. P. & Murphy, P. J., 1 Oct 2014, In: Planta Medica. 80, p. 1460

    Research output: Contribution to journal › Article › peer-review

  5. Published

    Marine guanidine derivatives affect the redox biology of Leishmania infantum and downregulate cytokines of macrophages

    Tempone, A. G., Martins, L. F., Bennett, E. L., Black, G. P. & Murphy, P. J., 1 Nov 2015, In: Planta Medica. 81, 16, p. 1470-1471

    Research output: Contribution to journal › Article › peer-review

  6. Published

    Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula

    Santos, M. F., Harper, P. M., Williams, D. E., Mesquita, J. T., Pinto, E. G., da Costa-Villa, T. A., Hajdu, E., Ferreira, A. G., Santos, R. A., Murphy, P. J., Anderson, R. J., Tempone, A. G. & Berlinck, R. G., 29 Apr 2015, In: Journal of natural products. 78, 5, p. 1101-1112

    Research output: Contribution to journal › Article › peer-review

  7. Published

    A study of polymethoxy-1-alkenes in Raphidiopsis (Cylindrospermopsis) raciborskii and Aphanizomenon gracile isolated in Poland

    Rzymskic, P., Evans, D., Murphy, P. & Kokocinski, M., 5 Dec 2019, In: Toxicon. 171, p. 51-53

    Research output: Contribution to journal › Article › peer-review

  8. Published

    Short synthesis of the furanofuran sub-unit of the toxin erythroskyrine

    Rossin, R., Jones, P. R., Murphy, P. J. & Worsley, W. R., 1996, In: Journal of the Chemical Society: Perkin Transactions 2. 12, p. 1323-1325 3 p.

    Research output: Contribution to journal › Article › peer-review

  9. Published

    Synthesis and Photoreactivity of 4,5-Dithienyl[1,3]dithiol-2-ones.

    Robert-Bleming, S. J., Davies, G. L., Kalaji, M., Murphy, P. J., Celli, A. M., Donati, D. & Ponticelli, F., 1 Aug 2003, In: Journal of Organic Chemistry. 68, 18, p. 7115-7118

    Research output: Contribution to journal › Article › peer-review

  10. Published

    Langmuir and Langmuir-Blodgett (LB) films of 4-dicyanomethylene,4H-cyclopenta[2,1-b,3,4-b?]dithiophene

    Riul, A., Taylor, D. M., Mills, C. A. & Murphy, P. J., May 2000, In: Thin Solid Films. 366, 1-2, p. 249-254 6 p.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Assessing the scope of the tandem Michael/intramolecular aldol reaction mediated by secondary amines, thiols and phosphines

    Richards, E. L., Murphy, P. J., Dinon, F., Fratucello, S., Brown, P. M., Gelbrich, T. & Hursthouse, M. B., 3 Sept 2001, In: Tetrahedron. 57, 36, p. 7771-7784

    Research output: Contribution to journal › Article › peer-review

  12. Published

    Slight changes in the chemical structure of haemanthamine greatly influence the effect of the derivatives on rumen fermentation in vitro

    Ramos-Morales, E., Braganca, R., Murphy, P., Tibble-Howlings, J. & Newbold, C. J., 21 Feb 2019, In: Scientific Reports. 8 p.

    Research output: Contribution to journal › Article › peer-review

  13. Epoxy-silanes in organic synthesis

    Procter, G., Russell, A. T., Murphy, P. J., Tan, T. S. & Mather, A. N., 1988, In: Tetrahedron. 44, 13, p. 3953-3973 21 p.

    Research output: Contribution to journal › Article › peer-review

  14. Published

    Organophosphorus Reagents.

    Murphy, P. J. (Editor), 1 Jan 2004, 2004 ed. Oxford University Press.

    Research output: Book/Report › Book

  15. Published

    Allylsilanes in organic synthesis; stereoselective preparation and reactions of functionalised β,γ-epoxysilanes

    Murphy, P. J., Russell, A. T. & Procter, G., 1990, In: Tetrahedron Letters. 31, 7, p. 1055-1058 4 p.

    Research output: Contribution to journal › Article › peer-review

  16. Published

    Synthetic studies towards ptilomycalin A using a biomimetic approach

    Murphy, P. J., Williams, H. L., Hursthouse, M. B. & Malik, K. M. A., 1994, In: Journal of the Chemical Society, Chemical Communications. 1, p. 119-120 2 p.

    Research output: Contribution to journal › Article › peer-review

  17. Published

    Synthesis of a pentacyclic model of ptilomycalin A

    Murphy, P. J. & Williams, H. L., 1994, In: Journal of the Chemical Society, Chemical Communications. 7, p. 819-820 2 p.

    Research output: Contribution to journal › Article › peer-review

  18. Allylsilanes in organic synthesis; An approach to the stereoselective synthesis of units for natural product synthesis

    Murphy, P. J. & Procter, G., 1990, In: Tetrahedron Letters. 31, 7, p. 1059-1062 4 p.

    Research output: Contribution to journal › Article › peer-review

  19. Published

    A synthesis of goniofufurone

    Murphy, P. J., 1992, In: Journal of the Chemical Society, Chemical Communications. 16, p. 1096-1097 2 p.

    Research output: Contribution to journal › Article › peer-review

  20. Published

    The total synthesis of Goniofufurone

    Murphy, P. J. & Dennison, S. T., 23 Jul 1993, In: Tetrahedron. 49, 30, p. 6695-6700 6 p.

    Research output: Contribution to journal › Article › peer-review

  21. Published

    Crystallographic evidence for the proposed host behaviour of ptilomycalin A

    Murphy, P. J., Williams, H. L., Hibbs, D. E., Hursthouse, M. B. & Abdul Malik, K. M., 1996, In: Chemical Communications. 3, p. 445-447 3 p.

    Research output: Contribution to journal › Article › peer-review

  22. The Wittig olefination reaction with carbonyl compounds other than aldehydes and ketones

    Murphy, P. J. & Brennan, J., 1988, In: Chemical Society Reviews. 17, p. 1-30 30 p.

    Research output: Contribution to journal › Article › peer-review

  23. Published

    2 Synthetic methods: Part (iv) Heteroatom methods

    Murphy, P. J., 1998, In: Annual Reports on the Progress of Chemistry - Section B. 94, p. 51-75 25 p.

    Research output: Contribution to journal › Article › peer-review

  24. Published

    Synthetic methods: Part (iv) Heteroatom methods

    Murphy, P. J., 1999, In: Annual Reports on the Progress of Chemistry - Section B. 1999, 95, p. 59-81 23 p.

    Research output: Contribution to journal › Article › peer-review

  25. Published

    Biomimetic model studies towards ptilomycalin A

    Murphy, P. J., Williams, H. L., Hibbs, D. E., Hursthouse, M. B. & Malik, K. M. A., 10 Jun 1996, In: Tetrahedron. 52, 24, p. 8315-8332 18 p.

    Research output: Contribution to journal › Article › peer-review

  26. Published

    Recent synthetic applications of the non-classical wittig reaction

    Murphy, P. J. & Lee, S. E., 1999, In: Journal of the Chemical Society: Perkin Transactions 1. 21, p. 3049-3066 18 p.

    Research output: Contribution to journal › Article › peer-review

  27. Published

    2 Synthetic methods. Part (iii) Heteroatom methods

    Murphy, P. J. & Thomas, D. A., 2000, In: Annual Reports on the Progress of Chemistry - Section B. 2000, 96, p. 39-63 25 p.

    Research output: Contribution to journal › Article › peer-review

  28. Published

    The synthesis and biological activity of the marine metabolite cylindrospermopsin

    Murphy, P. J. & Thomas, C. W., 1 Sept 2001, In: Chemical Society Reviews. 30, 5, p. 303-312

    Research output: Contribution to journal › Article › peer-review

  29. Allylsilanes in organic synthesis; convenient preparation of synthetic intermediates by catalytic hydrosilation of acetylenic alcohols

    Murphy, P. J., Spencer, J. L. & Procter, G., 1990, In: Tetrahedron Letters. 31, 7, p. 1051-1054 4 p.

    Research output: Contribution to journal › Article › peer-review

  30. Published

    Elucidating cylindrospermopsin toxicity via synthetic analogues: An in vitro approach

    Murphy, P., Evans, D., Hughes , J., Jones, L., Falfushynska, H., Horyn, O., Sokolova, I., Christensen, J., Coles, S. & Rzymskic, P., Nov 2019, In: Chemosphere. 234, p. 139-147 9 p.

    Research output: Contribution to journal › Article › peer-review

  31. Published

    Preparation of an ABC tricyclic model of the cylindrospermopsin alkaloids via a biomimetically inspired pathway

    Murphy, P. J., Evans, D. M., Horton, P. N. & Hursthouse, M. B., 28 Apr 2014, In: RSC Advances. 4, 40, p. 20744-20751

    Research output: Contribution to journal › Article › peer-review

  32. Published

    A convenient preparation of (1R, 2S, 7S, 8R)-3,5-diaza-2,7-dimethyl-1,8-diphenyloctan-1,8-diol and its enantiomer

    Murphy, P. J., Pinato, S., Thomas, D. & Oller-Lopez, J. L., 1 Sept 2006, In: Chemical and Pharmaceutical Bulletin. 54, 9, p. 1331-1332

    Research output: Contribution to journal › Article › peer-review

  33. Stereoselective aldol reactions via titanium enolates

    Murphy, P. J., Procter, G. & Russell, A. T., 1987, In: Tetrahedron Letters. 28, 18, p. 2037-2039 3 p.

    Research output: Contribution to journal › Article › peer-review

  34. Published

    Synthesis of Zephycandidine A from Haemanthamine

    Murphy, P., Tibble-Howlings, J., Kowalczyk, R. M. & Stevens, K., 16 Apr 2020, In: Tetrahedron Letters. 61, 16, 151785.

    Research output: Contribution to journal › Article › peer-review

  35. Published

    Synthetic studies towards ptilomycalin A: total synthesis of crambescidin 359

    Moore, C. G., Murphy, P. J., Williams, H. L., McGown, A. T. & Smith, N. K., 19 Nov 2007, In: Tetrahedron. 63, 47, p. 11771-11780

    Research output: Contribution to journal › Article › peer-review

  36. Published

    A synthesis of crambescidin 359.

    Moore, C. G., Murphy, P. J., Williams, H. L., McGown, A. T. & Smith, N. K., 6 Jan 2003, In: Tetrahedron Letters. 44, 2, p. 251-254

    Research output: Contribution to journal › Article › peer-review

  37. Published

    Dilithiated aminoalcohols as homochiral bases

    Milne, D. & Murphy, P. J., 1993, In: Journal of the Chemical Society, Chemical Communications. 10, p. 884-886 3 p.

    Research output: Contribution to journal › Article › peer-review

  38. Published

    Investigations into a low band gap, semiconducting polymer

    Mills, C. A., Taylor, D. M., Murphy, P. J., Dalton, C., Jones, G. W., Hall, L. M. & Hughes, A. V., Jun 1999, In: Synthetic Metals. 102, 1-3, p. 1000-1001 2 p.

    Research output: Contribution to journal › Article › peer-review

  39. Published

    Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes

    Martins, L. F., Mesquita, J. T., Pinto, E. G., Costa-Silva, T. A., Borborema, S. E. T., Galisteo Junior, A. J., Neves, B. J., Andrade, C. H., Bennett, E., Black, G., Harper, P., Evans, D., Fituri, H., Leyland, J. P., Martin, C., Roberts, T., Thornhill, A. J., Vale, S., Howard-Jones, A., Thomas, D., Williams, H. L., Overman, L., Berlinck, R., Murphy, P. & Tempone, A., 16 Sept 2016, In: Journal of natural products. 79, 9, p. 2202-2210 9 p.

    Research output: Contribution to journal › Article › peer-review

  40. Published

    Dye-sensitized solar cells (DSSCs) based on poly(3-hexylthioacetate thiophene)

    Manji, A. J. & Murphy, P. J., 9 Jan 2013, In: International Journal of Physical Sciences. 8, 1, p. 16-26

    Research output: Contribution to journal › Article › peer-review

  41. Published

    4,4-Dimethyl-3,5,8,10-tetraoxatricyclo[5.2.1.0(2,6)] decane.

    Light, M. E., Murphy, P. J., Brown, P. M. & Hursthouse, M. B., 1 May 2002, In: Acta Crystallographica Section E: Structure Reports Online. 58, 5, p. o560-o561

    Research output: Contribution to journal › Article › peer-review

  42. Published

    Ethyl 3-(diphenylphosphinoyl)-3-phenylpropionate.

    Light, M. E., Murphy, P. J., Hancock, P. & Hursthouse, M. B., 1 Sept 2002, In: Acta Crystallographica Section E: Structure Reports Online. 58, 9, p. o990-o991

    Research output: Contribution to journal › Article › peer-review

  43. Published

    Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp.

    Lazaro, J. E., Nitcheu, J., Mahmoudi, N., Ibana, J. A., Mangalindan, G. C., Black, G. P., Howard-Jones, A. G., Moore, C. G., Thomas, D. A., Mazier, D., Ireland, C. M., Concepcion, G. P., Murphy, P. J. & Diquet, B., 1 Oct 2006, In: Journal of Antibiotics. 59, 9, p. 583-590

    Research output: Contribution to journal › Article › peer-review

  44. Published

    Spectroelectrochemistry of bridged dithienyl derived polymers

    Kalaji, M., Murphy, P. J. & Williams, G. O., May 1999, In: Synthetic Metals. 101, 1, p. 123

    Research output: Contribution to journal › Article › peer-review

  45. Published

    Study of conducting polymers for use as redox supercapacitors

    Kalaji, M., Murphy, P. J. & Williams, G. O., Jun 1999, In: Synthetic Metals. 102, 1-3, p. 1360-1361 2 p.

    Research output: Contribution to journal › Article › peer-review

  46. Published

    Convenient synthesis of silyl substituted butadienes; a new route to silicon tethered intramolecular Diels-Alder reaction precursors

    Kahle, K., Murphy, P. J., Scott, J. & Tamagni, R., 1997, In: Journal of the Chemical Society: Perkin Transactions 1. 7, p. 997-1000

    Research output: Contribution to journal › Article › peer-review

  47. Published

    Synthesis of a novel C2-symmetric guanidine base

    Howard-Jones, A., Murphy, P. J. & Thomas, D. A., 15 Jan 1999, In: Journal of Organic Chemistry. 64, 3, p. 1039-1041 3 p.

    Research output: Contribution to journal › Article › peer-review

  48. Published

    The guanidine metabolites of Ptilocaulis spiculifer and related compounds; isolation and synthesis

    Heys, L., Moore, C. G. & Murphy, P. J., 2000, In: Chemical Society Reviews. 29, 1, p. 57-67 11 p.

    Research output: Contribution to journal › Article › peer-review

  49. Published

    Intramolecular Wittig reactions with lactones utilising triphenylphosphine and dimethyl acetylenedicarboxylate

    Heys, L., Murphy, P. J., Coles, S. J., Gelbrich, T. & Hursthouse, M. B., 24 Sept 1999, In: Tetrahedron Letters. 40, 39, p. 7151-7152 2 p.

    Research output: Contribution to journal › Article › peer-review

  50. Published

    Polymethoxy-1-Alkenes Screening of Chlorella and Spirulina Food Supplements Coupled with In Vivo Toxicity Studies

    Henao, E., Murphy, P., Falfushynska, H., Horyn, O., Evans, D. & Rzymski, P., Feb 2020, In: Toxins. 12, 2, 111.

    Research output: Contribution to journal › Article › peer-review

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