Dr Paddy Murphy

Reader in Organic Chemistry

Contact info

Dr Patrick J. Murphy

School of Natrual Sciences 

Alun Roberts Building

Bangor

LL57 2UW

Tel: 01248 382375

Email:  chs027@bangor.ac.uk

  1. Article › Research › Peer-reviewed
  2. Published

    2 Synthetic methods. Part (iii) Heteroatom methods

    Murphy, P. J. & Thomas, D. A., 2000, In : Annual Reports on the Progress of Chemistry - Section B. 2000, 96, p. 39-63 25 p.

    Research output: Contribution to journalArticle

  3. Published

    2 Synthetic methods: Part (iv) Heteroatom methods

    Murphy, P. J., 1998, In : Annual Reports on the Progress of Chemistry - Section B. 94, p. 51-75 25 p.

    Research output: Contribution to journalArticle

  4. Published

    2-Ethyl 5-methyl 3-hydroxythiophene-2,5-dicarboxylate.

    Coles, S. J., Guthmann, H., Hursthouse, M. B. & Murphy, P. J., 1 Oct 2001, In : Acta Crystallographica Section E: Structure Reports Online. 57, 10, p. o976-o977

    Research output: Contribution to journalArticle

  5. Published

    4,4-Dimethyl-3,5,8,10-tetraoxatricyclo[5.2.1.0(2,6)] decane.

    Light, M. E., Murphy, P. J., Brown, P. M. & Hursthouse, M. B., 1 May 2002, In : Acta Crystallographica Section E: Structure Reports Online. 58, 5, p. o560-o561

    Research output: Contribution to journalArticle

  6. Published

    4,4′,5,5′-Tetrakis(2-thienyl)tetrathiafulvalene [TT-TTF]: synthesis and first X-ray crystal structure of a thiophene-substituted TTF electron donor

    Charlton, A., Underhill, A. E., Williams, G., Kalaji, M., Murphy, P. J., Hibbs, D. E., Hursthouse, M. B. & Malik, K. M. A., 1996, In : Chemical Communications. 1996, 21, p. 2423-2424 2 p.

    Research output: Contribution to journalArticle

  7. Published

    4,5,4 ' 5 '-Tetrakis(2-methyl-thiopen-3-yl)-[2,2 ']bi[[1,3]dithiolylidene]

    Gelbrich, T., Roberts-Bleming, S. J., Kalaji, M., Murphy, P. J. & Hursthouse, M. B., 1 Dec 2001, In : Acta Crystallographica Section E: Structure Reports Online. 57, 12, p. o1143-o1144

    Research output: Contribution to journalArticle

  8. Published

    A biomimetic approach to the cylindrospermopsin alkaloids

    Evans, D. M. & Murphy, P. J., 21 Mar 2011, In : Chemical Communications. 47, 11, p. 3225-3226 2 p.

    Research output: Contribution to journalArticle

  9. Published

    A convenient preparation of (1R, 2S, 7S, 8R)-3,5-diaza-2,7-dimethyl-1,8-diphenyloctan-1,8-diol and its enantiomer

    Murphy, P. J., Pinato, S., Thomas, D. & Oller-Lopez, J. L., 1 Sep 2006, In : Chemical and Pharmaceutical Bulletin. 54, 9, p. 1331-1332

    Research output: Contribution to journalArticle

  10. Published

    A novel stereoselective route to ?-butyrolactones

    Casey, M., Manage, A. C. & Murphy, P. J., 11 Feb 1992, In : Tetrahedron Letters. 33, 7, p. 965-968 4 p.

    Research output: Contribution to journalArticle

  11. A phosphorane mediated synthesis of tetronic, thiotetronic and tetramic lactones

    Brennan, J. & Murphy, P. J., 1988, In : Tetrahedron Letters. 29, 17, p. 2063-2065 3 p.

    Research output: Contribution to journalArticle

  12. Published

    A short synthetic route to the tricyclic guanidinium core of the batzelladine alkaloids

    Black, G. P., Murphy, P. J. & Walshe, N. D. A., Aug 1998, In : Tetrahedron. 54, 32, p. 9481-9488 8 p.

    Research output: Contribution to journalArticle

  13. Published

    A study of polymethoxy-1-alkenes in Raphidiopsis (Cylindrospermopsis) raciborskii and Aphanizomenon gracile isolated in Poland

    Rzymskic, P., Evans, D., Murphy, P. & Kokocinski, M., 5 Dec 2019, In : Toxicon. 171, p. 51-53

    Research output: Contribution to journalArticle

  14. Published

    A synthesis of crambescidin 359.

    Moore, C. G., Murphy, P. J., Williams, H. L., McGown, A. T. & Smith, N. K., 6 Jan 2003, In : Tetrahedron Letters. 44, 2, p. 251-254

    Research output: Contribution to journalArticle

  15. Published

    A synthesis of goniofufurone

    Murphy, P. J., 1992, In : Journal of the Chemical Society, Chemical Communications. 16, p. 1096-1097 2 p.

    Research output: Contribution to journalArticle

  16. Published

    A synthesis of tiruchanduramine and a reinvestigation of its glycosidase inhibitory activity

    Buck, M., Evans, D., Evans, V. A., Herkt, D., Sharp, H., Hollinshead, J., Mitschang, F., Murphy, P., Nash, R. J. & Wenbourne, J., 3 Aug 2017, In : Tetrahedron. 73, 31, p. 4545-4548

    Research output: Contribution to journalArticle

  17. Published

    A synthetic approach to the plakortones

    Bittner, C., Burgo, A., Murphy, P. J., Sung, C. H. & Thornhill, A. J., 23 Apr 1999, In : Tetrahedron Letters. 40, 17, p. 3455-3456 2 p.

    Research output: Contribution to journalArticle

  18. Allylsilanes in organic synthesis; An approach to the stereoselective synthesis of units for natural product synthesis

    Murphy, P. J. & Procter, G., 1990, In : Tetrahedron Letters. 31, 7, p. 1059-1062 4 p.

    Research output: Contribution to journalArticle

  19. Allylsilanes in organic synthesis; convenient preparation of synthetic intermediates by catalytic hydrosilation of acetylenic alcohols

    Murphy, P. J., Spencer, J. L. & Procter, G., 1990, In : Tetrahedron Letters. 31, 7, p. 1051-1054 4 p.

    Research output: Contribution to journalArticle

  20. Published

    Allylsilanes in organic synthesis; stereoselective preparation and reactions of functionalised β,γ-epoxysilanes

    Murphy, P. J., Russell, A. T. & Procter, G., 1990, In : Tetrahedron Letters. 31, 7, p. 1055-1058 4 p.

    Research output: Contribution to journalArticle

  21. Published

    An intramolecular Baylis-Hillman reaction catalysed by secondary amines

    Black, G. P., Dinon, F., Fratucello, S., Murphy, P. J., Nielsen, M., Williams, H. L. & Walshe, N. D. A., 8 Dec 1997, In : Tetrahedron Letters. 38, 49, p. 8561-8564 4 p.

    Research output: Contribution to journalArticle

  22. Published

    Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes

    Martins, L. F., Mesquita, J. T., Pinto, E. G., Costa-Silva, T. A., Borborema, S. E. T., Galisteo Junior, A. J., Neves, B. J., Andrade, C. H., Bennett, E., Black, G., Harper, P., Evans, D., Fituri, H., Leyland, J. P., Martin, C., Roberts, T., Thornhill, A. J., Vale, S., Howard-Jones, A., Thomas, D., Williams, H. L., Overman, L., Berlinck, R., Murphy, P. & Tempone, A., 16 Sep 2016, In : Journal of natural products. 79, 9, p. 2202-2210 9 p.

    Research output: Contribution to journalArticle

  23. Published

    Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula

    Santos, M. F., Harper, P. M., Williams, D. E., Mesquita, J. T., Pinto, E. G., da Costa-Villa, T. A., Hajdu, E., Ferreira, A. G., Santos, R. A., Murphy, P. J., Anderson, R. J., Tempone, A. G. & Berlinck, R. G., 29 Apr 2015, In : Journal of natural products. 78, 5, p. 1101-1112

    Research output: Contribution to journalArticle

  24. Published

    Antimalarial activity of crambescidin 800 and synthetic analogues against liver and blood stage of Plasmodium sp.

    Lazaro, J. E., Nitcheu, J., Mahmoudi, N., Ibana, J. A., Mangalindan, G. C., Black, G. P., Howard-Jones, A. G., Moore, C. G., Thomas, D. A., Mazier, D., Ireland, C. M., Concepcion, G. P., Murphy, P. J. & Diquet, B., 1 Oct 2006, In : Journal of Antibiotics. 59, 9, p. 583-590

    Research output: Contribution to journalArticle

  25. Published

    Assessing the scope of the tandem Michael/intramolecular aldol reaction mediated by secondary amines, thiols and phosphines

    Richards, E. L., Murphy, P. J., Dinon, F., Fratucello, S., Brown, P. M., Gelbrich, T. & Hursthouse, M. B., 3 Sep 2001, In : Tetrahedron. 57, 36, p. 7771-7784

    Research output: Contribution to journalArticle

  26. Published

    Biomimetic model studies towards ptilomycalin A

    Murphy, P. J., Williams, H. L., Hibbs, D. E., Hursthouse, M. B. & Malik, K. M. A., 10 Jun 1996, In : Tetrahedron. 52, 24, p. 8315-8332 18 p.

    Research output: Contribution to journalArticle

  27. Published

    Characterization of the hydrides in Stryker's reagent: [HCuP(C 6H5)3]6

    Bennett, E. L., Murphy, P. J., Imberti, S. & Parker, S. F., 26 Feb 2014, In : Inorganic Chemistry. 53, 6, p. 2963-2967 5 p.

    Research output: Contribution to journalArticle

  28. Published

    Convenient synthesis of silyl substituted butadienes; a new route to silicon tethered intramolecular Diels-Alder reaction precursors

    Kahle, K., Murphy, P. J., Scott, J. & Tamagni, R., 1997, In : Journal of the Chemical Society: Perkin Transactions 1. 7, p. 997-1000

    Research output: Contribution to journalArticle

  29. Published

    Crystallographic evidence for the proposed host behaviour of ptilomycalin A

    Murphy, P. J., Williams, H. L., Hibbs, D. E., Hursthouse, M. B. & Abdul Malik, K. M., 1996, In : Chemical Communications. 3, p. 445-447 3 p.

    Research output: Contribution to journalArticle

  30. Published

    Cyclisation reactions of bis-protected guanidines.

    Albrecht, C., Barnes, S., Bockemeier, H., Davies, D., Dennis, M., Evans, D. M., Fletcher, M. D., Jones, I., Leitmann, V., Murphy, P. J., Rowles, R., Nash, R., Stephenson, R. A., Horton, P. N. & Hursthouse, M. B., 1 Jan 2008, In : Tetrahedron Letters. 49, 1, p. 185-188

    Research output: Contribution to journalArticle

  31. Published

    Dilithiated aminoalcohols as homochiral bases

    Milne, D. & Murphy, P. J., 1993, In : Journal of the Chemical Society, Chemical Communications. 10, p. 884-886 3 p.

    Research output: Contribution to journalArticle

  32. Published

    Disparity in the tandem epoxide-allylic alcohol-[1,2]/[2,3]-Wittig rearrangement of cis- and trans-1-benzyloxy-3,4-epoxycyclopentane

    Brookes, P. C., Murphy, P. J., Sommer, K., Hibbs, D. E., Hursthouse, M. B. & Malik, K. M. A., 1998, In : Journal of the Chemical Society: Perkin Transactions 1. 12, p. 1899-1901 3 p.

    Research output: Contribution to journalArticle

  33. Published

    Dye-sensitized solar cells (DSSCs) based on poly(3-hexylthioacetate thiophene)

    Manji, A. J. & Murphy, P. J., 9 Jan 2013, In : International Journal of Physical Sciences. 8, 1, p. 16-26

    Research output: Contribution to journalArticle

  34. Published

    Electropolymerization Studies on a Series of Thiophene-Substituted 1,3-Dithiole-2-ones: Solid-State Preparation of a Novel TTF-Derivatized Polythiophene.

    Anjos, T., Charlton, A., Coles, S. J., Croft, A. K., Hursthouse, M. B., Kalaji, M., Murphy, P. J. & Roberts-Bleming, S. J., 14 Apr 2009, In : Macromolecules. 42, 7, p. 2505-2515

    Research output: Contribution to journalArticle

  35. Published

    Elucidating cylindrospermopsin toxicity via synthetic analogues: An in vitro approach

    Murphy, P., Evans, D., Hughes, J., Jones, L., Falfushynska, H., Horyn, O., Sokolova, I., Christensen, J., Coles, S. & Rzymskic, P., Nov 2019, In : Chemosphere. 234, p. 139-147 9 p.

    Research output: Contribution to journalArticle

  36. Published

    Epoxide rearrangements using dilithiated aminoalcohols as chiral bases.

    Brookes, P. C., Milne, D. J., Murphy, P. J. & Spolaore, B., 3 Jun 2002, In : Tetrahedron. 58, 23, p. 4675-4680

    Research output: Contribution to journalArticle

  37. Epoxy-silanes in organic synthesis

    Procter, G., Russell, A. T., Murphy, P. J., Tan, T. S. & Mather, A. N., 1988, In : Tetrahedron. 44, 13, p. 3953-3973 21 p.

    Research output: Contribution to journalArticle

  38. Published

    Ethyl 3-(diphenylphosphinoyl)-3-phenylpropionate.

    Light, M. E., Murphy, P. J., Hancock, P. & Hursthouse, M. B., 1 Sep 2002, In : Acta Crystallographica Section E: Structure Reports Online. 58, 9, p. o990-o991

    Research output: Contribution to journalArticle

  39. Published

    Highly stereoselective conjugate additions of heteroaryl alkyl sulfoxides

    Casey, M., Gairns, R. S., Geraghty, G. M., Kelly, C. J., Murphy, P. J. & Walker, A. J., 2000, In : Synlett. 2000, 12, p. 1721-1724 4 p.

    Research output: Contribution to journalArticle

  40. Published

    How the Surface Structure Determines the Properties of CuH

    Bennett, E. L., Bennett, E., Wilson, T., Murphy, P. J., Refson, K., Hannon, A. C., Imberti, S., Callear, S. K., Chass, G. A. & Parker, S. F., 11 Feb 2015, In : Inorganic Chemistry. 54, 5, p. 2213-2220

    Research output: Contribution to journalArticle

  41. Published

    Intramolecular Wittig reactions with esters utilising triphenylphosphine and dimethyl acetylenedicarboxylate

    Evans, L. A., Griffiths, K. E., Guthmann, H. & Murphy, P. J., 7 Jan 2002, In : Tetrahedron Letters. 43, 2, p. 299-301

    Research output: Contribution to journalArticle

  42. Published

    Intramolecular Wittig reactions with lactones utilising triphenylphosphine and dimethyl acetylenedicarboxylate

    Heys, L., Murphy, P. J., Coles, S. J., Gelbrich, T. & Hursthouse, M. B., 24 Sep 1999, In : Tetrahedron Letters. 40, 39, p. 7151-7152 2 p.

    Research output: Contribution to journalArticle

  43. Published

    Intramolecular epoxide ring opening cyclisation reactions involving guanidines

    Al-Shuhaib, Z., Arndt, M., Dennis, M., Evans, D., Jones, I., Leitmann, V., Murphy, P., Roberts, D., Rowles, R., Sadaghiani, Y. K., Thornhill, A. J., Nash, R. J., Hollinshead, J., Bartholomew, B., Tizzard, G. & Coles, S., 16 Feb 2017, In : Tetrahedron. 73, 7, p. 845-852 8 p.

    Research output: Contribution to journalArticle

  44. Published

    Intramolecular guanidine epoxide ring opening reactions.

    Dennis, M., Hall, L. M., Murphy, P. J., Thornhill, A. J., Nash, R., Winters, A. L., Hursthouse, M. B., Light, M. E. & Horton, P., 7 Apr 2003, In : Tetrahedron Letters. 44, 15, p. 3075-3080

    Research output: Contribution to journalArticle

  45. Published

    Intramolecular palladium mediated π-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

    Al-Shuhaib, Z. A., Doerksen, E., Page, J. M., Al-Shuhaiba, Z., Böckemeier, H., Coghlan, L., Dörksena, E., Jones, I. V., Murphy, P. J. & Nash, R. P., 27 Sep 2013, In : Tetrahedron Letters. 54, 49, p. 6716-6718

    Research output: Contribution to journalArticle

  46. Published

    Investigations into a low band gap, semiconducting polymer

    Mills, C. A., Taylor, D. M., Murphy, P. J., Dalton, C., Jones, G. W., Hall, L. M. & Hughes, A. V., Jun 1999, In : Synthetic Metals. 102, 1-3, p. 1000-1001 2 p.

    Research output: Contribution to journalArticle

  47. Published

    Iodocyclisation and rearrangement reactions of mono-protected allyl substituted guanidines.

    Davies, D., Fletcher, M. D., Franken, H., Hollinshead, J., Kahm, K., Murphy, P. J., Nash, R. & Potter, D. M., 29 Dec 2010, In : Tetrahedron Letters. 51, 52, p. 6825-6829

    Research output: Contribution to journalArticle

  48. Published

    Iodocyclisations reactions of Boc- and Cbz-protected N-allylguanidines

    Al-Shuhaib, Z. A., Al Shuhaiba, Z., Davies, D. H., Dennis, M., Evans, D. M., Fletcher, M. D., Franken, H., Hancock, P., Hollinshead, J., Jones, I., Kähm, K., Murphy, P. J., Nash, R. P. & Rowles, R., 15 Apr 2014, In : Tetrahedron. 70, 29, p. 4412-4419

    Research output: Contribution to journalArticle

  49. Published

    Langmuir and Langmuir-Blodgett (LB) films of 4-dicyanomethylene,4H-cyclopenta[2,1-b,3,4-b?]dithiophene

    Riul, A., Taylor, D. M., Mills, C. A. & Murphy, P. J., May 2000, In : Thin Solid Films. 366, 1-2, p. 249-254 6 p.

    Research output: Contribution to journalArticle

  50. Published

    Marine guanidine derivatives affect the redox biology of Leishmania infantum and downregulate cytokines of macrophages

    Tempone, A. G., Martins, L. F., Bennett, E. L., Black, G. P. & Murphy, P. J., 1 Nov 2015, In : Planta Medica. 81, 16, p. 1470-1471

    Research output: Contribution to journalArticle

  51. Published

    Michael and substitution reactions of bicyclic tetronic, tetramic and thiotetronic esters

    Bertucco, A., Brennan, J., Fachini, M., Kluge, S., J. Murphy, P., Pasutto, F., Signorini, R. & Lloyd Williams, H., 1994, In : Tetrahedron. 50, 27, p. 8237-8252 16 p.

    Research output: Contribution to journalArticle

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