• Y. Ning
  • C. Multari
  • X. Luo
  • C. Palego
  • D. Molinero
  • X. Cheng
  • J.C. Hwang
  • C. Merla
An improved microchamber for electrical detection of biological cells was designed, fabricated and tested. The microchamber was formed between a gold coplanar stripline fabricated on a sapphire microscope slide and a single microfluidic channel fabricated in a polydimethylsiloxane cover. Compared with the previous design of a coplanar waveguide on a quartz slide with multiple microfluidic channels, the present microchamber was more sensitive, compact, rugged, and transparent. Tests on Jurkat cells in both time and frequency domains demonstrated single-cell sensing potential, as well as discrimination of live vs. dead cells. The test results could be explained by a simple equivalent-circuit model, which efficiently de-embedded the intrinsic cell properties from solution and electrode effects.
Original languageEnglish
Publication statusPublished - 6 Oct 2013
EventEuropean Microwave Conference (EuMC), Nurember, October 2013 -
Duration: 3 Jan 0001 → …


ConferenceEuropean Microwave Conference (EuMC), Nurember, October 2013
Period3/01/01 → …
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