Electronic versions

  • Paul G Mullins
  • David J McGonigle
    Cardiff University
  • Ruth L O'Gorman
    University Children's Hospital, ZurichUniversity of Zurich
  • Nicolaas A J Puts
    Johns Hopkins UniversityKennedy Krieger Institute
  • Rishma Vidyasagar
    Manchester University
  • C John Evans
    Cardiff University
  • Richard A E Edden
    Johns Hopkins UniversityKennedy Krieger Institute
  • Cardiff Symposium on MRS of GABA
There is increasing interest in the use of edited proton magnetic resonance spectroscopy for the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a number of spectroscopy groups met to discuss the acquisition, analysis and interpretation of GABA-edited MR spectra. This paper aims to set out the issues discussed at this meeting, reporting areas of consensus around parameters and procedures in the field and highlighting those areas where differences remain. It is hoped that this paper can fulfill two needs, providing a summary of the current ‘state-of-the-art’ in the field of GABA-edited MRS at 3 T using MEGA-PRESS and a basic guide to help researchers new to the field to avoid some of the pitfalls inherent in the acquisition and processing of edited MRS for GABA.


  • Algorithms, Brain, Humans, Magnetic Resonance Spectroscopy, Reproducibility of Results, Sensitivity and Specificity, gamma-Aminobutyric Acid, Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review
Original languageEnglish
Pages (from-to)43-52
Number of pages10
Early online date13 Dec 2012
Publication statusPublished - 1 Feb 2014

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