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Cyclic guanidine containing amino acids that promote glucocerebrosidase

Research output: Contribution to journal › Article › peer-review

Standard Standard

Cyclic guanidine containing amino acids that promote glucocerebrosidase. / Al-Taie, Zahraa S.; Bartholomew, Barbara; Coles, Simon J. et al.
In: Tetrahedron, Vol. 123, 132959, 24.09.2022.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Al-Taie, ZS, Bartholomew, B, Coles, SJ, Evans, DM, Hollinshead, J, Jones, LF, Kraehenbuehl, R, Murphy, PJ, Nash, RJ, Penkova, YB & Tizzard, GJ 2022, 'Cyclic guanidine containing amino acids that promote glucocerebrosidase', Tetrahedron, vol. 123, 132959. https://doi.org/10.1016/j.tet.2022.132959

APA

Al-Taie, Z. S., Bartholomew, B., Coles, S. J., Evans, D. M., Hollinshead, J., Jones, L. F., Kraehenbuehl, R., Murphy, P. J., Nash, R. J., Penkova, Y. B., & Tizzard, G. J. (2022). Cyclic guanidine containing amino acids that promote glucocerebrosidase. Tetrahedron, 123, Article 132959. https://doi.org/10.1016/j.tet.2022.132959

CBE

Al-Taie ZS, Bartholomew B, Coles SJ, Evans DM, Hollinshead J, Jones LF, Kraehenbuehl R, Murphy PJ, Nash RJ, Penkova YB, et al. 2022. Cyclic guanidine containing amino acids that promote glucocerebrosidase. Tetrahedron. 123:Article 132959. https://doi.org/10.1016/j.tet.2022.132959

MLA

Al-Taie, Zahraa S. et al. "Cyclic guanidine containing amino acids that promote glucocerebrosidase". Tetrahedron. 2022. 123. https://doi.org/10.1016/j.tet.2022.132959

VancouverVancouver

Al-Taie ZS, Bartholomew B, Coles SJ, Evans DM, Hollinshead J, Jones LF et al. Cyclic guanidine containing amino acids that promote glucocerebrosidase. Tetrahedron. 2022 Sept 24;123:132959. doi: 10.1016/j.tet.2022.132959

Author

Al-Taie, Zahraa S. ; Bartholomew, Barbara ; Coles, Simon J. et al. / Cyclic guanidine containing amino acids that promote glucocerebrosidase. In: Tetrahedron. 2022 ; Vol. 123.

RIS

TY - JOUR

T1 - Cyclic guanidine containing amino acids that promote glucocerebrosidase

AU - Al-Taie, Zahraa S.

AU - Bartholomew, Barbara

AU - Coles, Simon J.

AU - Evans, Daniel M.

AU - Hollinshead, Jackie

AU - Jones, Leigh F.

AU - Kraehenbuehl, Rolf

AU - Murphy, Patrick J.

AU - Nash, Robert J.

AU - Penkova, Yana B.

AU - Tizzard, Graham J.

PY - 2022/9/24

Y1 - 2022/9/24

N2 - Novel cyclic guanidine containing amino acids (S)-1, 2 and 3 were prepared from l-serine 5. (S)-2-Imino-3-methylimidazolidine-4-carboxylic acid hydrochloride salt 2. HCl and (3S, 6S)-3,6-bis(hydroxymethyl)-1,4-dimethylpiperazine-2,5-dione 15 showed in vitro promotion of the enzyme glucocerebrosidase.

AB - Novel cyclic guanidine containing amino acids (S)-1, 2 and 3 were prepared from l-serine 5. (S)-2-Imino-3-methylimidazolidine-4-carboxylic acid hydrochloride salt 2. HCl and (3S, 6S)-3,6-bis(hydroxymethyl)-1,4-dimethylpiperazine-2,5-dione 15 showed in vitro promotion of the enzyme glucocerebrosidase.

KW - Cyclic guanidines

KW - Glycosidase inhibitors

KW - Glycosidase promoters

KW - -methylation

U2 - 10.1016/j.tet.2022.132959

DO - 10.1016/j.tet.2022.132959

M3 - Article

VL - 123

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

M1 - 132959

ER -