Fast, compact and label-free electrical detection of live and dead single cells

Research output: Contribution to conferencePaper

Electronic versions

  • Y. Ning
  • C.R. Multari
  • X. Luo
  • C. Merla
  • C. Palego
  • X. Cheng
  • J.C. Hwang
Using a novel broadband microchamber, electrical detection of live and dead single cells was demonstrated. Tests on Jurkat cells showed that live cells had lower resistance but higher capacitance than that of dead cells. The test results were compared with the limited literature on broadband electrical detection of single cells and the discrepancies, both qualitative and quantitative, were discussed. These results indicate that, while broadband electrical detection at the single-cell level is becoming feasible, many challenges remain in impedance match, calibration, sensitivity, cell manipulation, solution effect and modeling.
Original languageEnglish
DOIs
Publication statusPublished - 9 Dec 2013
EventMicrowave Workshop Series on RF and Wireless Technologies for Biomedical and Healthcare Applications (IMWS-BIO), 2013 IEEE MTT-S International, Singapore -
Duration: 3 Jan 0001 → …

Conference

ConferenceMicrowave Workshop Series on RF and Wireless Technologies for Biomedical and Healthcare Applications (IMWS-BIO), 2013 IEEE MTT-S International, Singapore
Period3/01/01 → …
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