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High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. / McGregor, Gordon; Nichols, Simon; Hamborg, Thomas; Bryning, Lucy; Edwards, Rhiannon; Markland, David; Mercer, Jenny; Birkett, Stefan; Ennis, Stewart; Powell, Richard; Begg, Brian; Haykowsky, Mark; Banerjee, Prithwish; Ingle, Lee; Shave, Rob; Backx, Karianne.

In: BMJ Open, Vol. 6, No. 11, 6:e012843, 18.11.2016, p. 1-9.

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McGregor, G, Nichols, S, Hamborg, T, Bryning, L, Edwards, R, Markland, D, Mercer, J, Birkett, S, Ennis, S, Powell, R, Begg, B, Haykowsky, M, Banerjee, P, Ingle, L, Shave, R & Backx, K 2016, 'High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation', BMJ Open, vol. 6, no. 11, 6:e012843, pp. 1-9. https://doi.org/10.1136/bmjopen-2016-012843

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McGregor, Gordon ; Nichols, Simon ; Hamborg, Thomas ; Bryning, Lucy ; Edwards, Rhiannon ; Markland, David ; Mercer, Jenny ; Birkett, Stefan ; Ennis, Stewart ; Powell, Richard ; Begg, Brian ; Haykowsky, Mark ; Banerjee, Prithwish ; Ingle, Lee ; Shave, Rob ; Backx, Karianne. / High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. In: BMJ Open. 2016 ; Vol. 6, No. 11. pp. 1-9.

RIS

TY - JOUR

T1 - High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation

AU - McGregor, Gordon

AU - Nichols, Simon

AU - Hamborg, Thomas

AU - Bryning, Lucy

AU - Edwards, Rhiannon

AU - Markland, David

AU - Mercer, Jenny

AU - Birkett, Stefan

AU - Ennis, Stewart

AU - Powell, Richard

AU - Begg, Brian

AU - Haykowsky, Mark

AU - Banerjee, Prithwish

AU - Ingle, Lee

AU - Shave, Rob

AU - Backx, Karianne

PY - 2016/11/18

Y1 - 2016/11/18

N2 - Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for coronary heart disease (CHD) and may not be the most appropriate strategy for the ‘modern’ patient with CHD. High-intensity interval training (HIIT) appears to be a safe and effective alternative, resulting in greater improvements in peak oxygen uptake (VO2 peak). To date, HIIT trials have predominantly been proof-of-concept studies in the laboratory setting and conducted outside the UK. The purpose of this multicentre randomised controlled trial is to compare the effects of HIIT and MISS training in patients with CHD attending UK CR programmes.

AB - Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for coronary heart disease (CHD) and may not be the most appropriate strategy for the ‘modern’ patient with CHD. High-intensity interval training (HIIT) appears to be a safe and effective alternative, resulting in greater improvements in peak oxygen uptake (VO2 peak). To date, HIIT trials have predominantly been proof-of-concept studies in the laboratory setting and conducted outside the UK. The purpose of this multicentre randomised controlled trial is to compare the effects of HIIT and MISS training in patients with CHD attending UK CR programmes.

KW - High intensity interval training; HIIT; cardiac rehabilitation

U2 - 10.1136/bmjopen-2016-012843

DO - 10.1136/bmjopen-2016-012843

M3 - Article

VL - 6

SP - 1

EP - 9

JO - BMJ Open

T2 - BMJ Open

JF - BMJ Open

SN - 2044-6055

IS - 11

M1 - 6:e012843

ER -