Immobilised Enzymes for Sesquiterpene Synthesis in Batch and Flow Systems

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  • Donya Valikhani
    Cardiff University
  • Prabhakar Srivastava
    Cardiff University
  • Rudolf K Allemann
    Cardiff University
  • Thomas Wirth
    Cardiff University
Sesquiterpene synthases catalyse the bioconversion of farnesyl diphosphate into sesquiterpenes. The immobilisation of sesquiterpene synthases on controlled porosity glass through metal-ion affinity binding is reported. The immobilised sesquiterpene synthases were able to maintain 50 % catalytic activity for at least 50 cycles under continuous flow conditions.
Original languageEnglish
JournalChemCatChem
Volume12
Issue number8
Early online date21 Jan 2020
DOIs
Publication statusPublished - 20 Apr 2020
Externally publishedYes
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