Improved broadband electrical detection of individual biological cells

Research output: Contribution to conferencePaper

Electronic versions

  • Y. Ning
  • X. Ma
  • C. Multari
  • X. Luo
  • V. Gholizadeb
  • C. Palego
  • X. Cheng
  • J. Hwang
Based on a homemade probe station on top of an inverted microscope for simultaneous microwave measurement and visual validation, broadband detection of live Jurkat cells was successfully extended from 2-3.5 GHz to 0.5-20 GHz with comparable sensitivity and reproducibility. With a carefully optimized coplanar waveguide, closely spaced microwave probes, and frequent calibrations, reference planes were established next to the microfluidic channel, which resulted in smooth and well-behaved scattering parameters without spurious resonances. From the measured scattering parameters, the extracted cytoplasm resistance of 190 kΩ was consistent with the previously reported value but validated over a much wider bandwidth.
Original languageEnglish
Publication statusPublished - 17 May 2015
EventIEEE International Microwave Symposium, Phoenix, USA, May 2015 -
Duration: 3 Jan 0001 → …


ConferenceIEEE International Microwave Symposium, Phoenix, USA, May 2015
Period3/01/01 → …
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