Improved broadband electrical detection of individual biological cells
Research output: Contribution to conference › Paper
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2015. 1-3 Paper presented at IEEE International Microwave Symposium, Phoenix, USA, May 2015.
Research output: Contribution to conference › Paper
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T1 - Improved broadband electrical detection of individual biological cells
AU - Ning, Y.
AU - Ma, X.
AU - Multari, C.
AU - Luo, X.
AU - Gholizadeb, V.
AU - Palego, C.
AU - Cheng, X.
AU - Hwang, J.
PY - 2015/5/17
Y1 - 2015/5/17
N2 - Based on a homemade probe station on top of an inverted microscope for simultaneous microwave measurement and visual validation, broadband detection of live Jurkat cells was successfully extended from 2-3.5 GHz to 0.5-20 GHz with comparable sensitivity and reproducibility. With a carefully optimized coplanar waveguide, closely spaced microwave probes, and frequent calibrations, reference planes were established next to the microfluidic channel, which resulted in smooth and well-behaved scattering parameters without spurious resonances. From the measured scattering parameters, the extracted cytoplasm resistance of 190 kΩ was consistent with the previously reported value but validated over a much wider bandwidth.
AB - Based on a homemade probe station on top of an inverted microscope for simultaneous microwave measurement and visual validation, broadband detection of live Jurkat cells was successfully extended from 2-3.5 GHz to 0.5-20 GHz with comparable sensitivity and reproducibility. With a carefully optimized coplanar waveguide, closely spaced microwave probes, and frequent calibrations, reference planes were established next to the microfluidic channel, which resulted in smooth and well-behaved scattering parameters without spurious resonances. From the measured scattering parameters, the extracted cytoplasm resistance of 190 kΩ was consistent with the previously reported value but validated over a much wider bandwidth.
U2 - 10.1109/MWSYM.2015.7166722
DO - 10.1109/MWSYM.2015.7166722
M3 - Paper
SP - 1
EP - 3
T2 - IEEE International Microwave Symposium, Phoenix, USA, May 2015
Y2 - 3 January 0001
ER -