Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome
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In: Homeopathy: the Journal of the Faculty of Homeopathy, Vol. 103, No. 3, 01.07.2014, p. 172-177.
Research output: Contribution to journal › Article › peer-review
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T1 - Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome
AU - Peckham, Emily J
AU - Relton, Clare
AU - Raw, Jackie
AU - Walters, Clare
AU - Thomas, Kate
AU - Smith, Christine
AU - Kapur, Kapil
AU - Said, Elmuhtady
N1 - Copyright © 2014 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.
PY - 2014/7/1
Y1 - 2014/7/1
N2 - Irritable bowel syndrome (IBS) is a chronic condition for which there is no consensus on the optimum treatment. Gastroenterology problems are some of the most common conditions treated by homeopaths, yet few trials have explored the effectiveness of individualised homeopathic treatment for IBS. A three-armed trial was conducted which compared: usual care, homeopathic treatment plus usual care and supportive listening plus usual care. The primary outcome was change in irritable bowel symptom severity score between baseline and 26 weeks, calculated using ANCOVA. An interim ANCOVA adjusted for baseline IBS severity, age and employment status found no statistically significant difference between the three arms. However, a post-hoc test comparing homeopathic treatment plus usual care to usual care alone found a statistically significant difference in favour of homeopathic treatment. In addition, 62.5 percent of patients in the homeopathic treatment arm (compared to 25.0 percent of those in the usual care arm), achieved a clinically relevant change in irritable bowel symptom severity score, which indicates a promising effect for homeopathic treatment, though these results should be interpreted with caution due to the low number of participants in the study.
AB - Irritable bowel syndrome (IBS) is a chronic condition for which there is no consensus on the optimum treatment. Gastroenterology problems are some of the most common conditions treated by homeopaths, yet few trials have explored the effectiveness of individualised homeopathic treatment for IBS. A three-armed trial was conducted which compared: usual care, homeopathic treatment plus usual care and supportive listening plus usual care. The primary outcome was change in irritable bowel symptom severity score between baseline and 26 weeks, calculated using ANCOVA. An interim ANCOVA adjusted for baseline IBS severity, age and employment status found no statistically significant difference between the three arms. However, a post-hoc test comparing homeopathic treatment plus usual care to usual care alone found a statistically significant difference in favour of homeopathic treatment. In addition, 62.5 percent of patients in the homeopathic treatment arm (compared to 25.0 percent of those in the usual care arm), achieved a clinically relevant change in irritable bowel symptom severity score, which indicates a promising effect for homeopathic treatment, though these results should be interpreted with caution due to the low number of participants in the study.
U2 - 10.1016/j.homp.2014.05.001
DO - 10.1016/j.homp.2014.05.001
M3 - Article
VL - 103
SP - 172
EP - 177
JO - Homeopathy: the Journal of the Faculty of Homeopathy
JF - Homeopathy: the Journal of the Faculty of Homeopathy
SN - 1475-4916
IS - 3
ER -