Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome

Research output: Contribution to journalArticlepeer-review

Standard Standard

Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome. / Peckham, Emily J; Relton, Clare; Raw, Jackie et al.
In: Homeopathy: the Journal of the Faculty of Homeopathy, Vol. 103, No. 3, 01.07.2014, p. 172-177.

Research output: Contribution to journalArticlepeer-review

HarvardHarvard

Peckham, EJ, Relton, C, Raw, J, Walters, C, Thomas, K, Smith, C, Kapur, K & Said, E 2014, 'Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome', Homeopathy: the Journal of the Faculty of Homeopathy, vol. 103, no. 3, pp. 172-177. https://doi.org/10.1016/j.homp.2014.05.001

APA

Peckham, E. J., Relton, C., Raw, J., Walters, C., Thomas, K., Smith, C., Kapur, K., & Said, E. (2014). Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome. Homeopathy: the Journal of the Faculty of Homeopathy, 103(3), 172-177. https://doi.org/10.1016/j.homp.2014.05.001

CBE

Peckham EJ, Relton C, Raw J, Walters C, Thomas K, Smith C, Kapur K, Said E. 2014. Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome. Homeopathy: the Journal of the Faculty of Homeopathy. 103(3):172-177. https://doi.org/10.1016/j.homp.2014.05.001

MLA

VancouverVancouver

Peckham EJ, Relton C, Raw J, Walters C, Thomas K, Smith C et al. Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome. Homeopathy: the Journal of the Faculty of Homeopathy. 2014 Jul 1;103(3):172-177. doi: 10.1016/j.homp.2014.05.001

Author

Peckham, Emily J ; Relton, Clare ; Raw, Jackie et al. / Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome. In: Homeopathy: the Journal of the Faculty of Homeopathy. 2014 ; Vol. 103, No. 3. pp. 172-177.

RIS

TY - JOUR

T1 - Interim results of a randomised controlled trial of homeopathic treatment for irritable bowel syndrome

AU - Peckham, Emily J

AU - Relton, Clare

AU - Raw, Jackie

AU - Walters, Clare

AU - Thomas, Kate

AU - Smith, Christine

AU - Kapur, Kapil

AU - Said, Elmuhtady

N1 - Copyright © 2014 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

PY - 2014/7/1

Y1 - 2014/7/1

N2 - Irritable bowel syndrome (IBS) is a chronic condition for which there is no consensus on the optimum treatment. Gastroenterology problems are some of the most common conditions treated by homeopaths, yet few trials have explored the effectiveness of individualised homeopathic treatment for IBS. A three-armed trial was conducted which compared: usual care, homeopathic treatment plus usual care and supportive listening plus usual care. The primary outcome was change in irritable bowel symptom severity score between baseline and 26 weeks, calculated using ANCOVA. An interim ANCOVA adjusted for baseline IBS severity, age and employment status found no statistically significant difference between the three arms. However, a post-hoc test comparing homeopathic treatment plus usual care to usual care alone found a statistically significant difference in favour of homeopathic treatment. In addition, 62.5 percent of patients in the homeopathic treatment arm (compared to 25.0 percent of those in the usual care arm), achieved a clinically relevant change in irritable bowel symptom severity score, which indicates a promising effect for homeopathic treatment, though these results should be interpreted with caution due to the low number of participants in the study.

AB - Irritable bowel syndrome (IBS) is a chronic condition for which there is no consensus on the optimum treatment. Gastroenterology problems are some of the most common conditions treated by homeopaths, yet few trials have explored the effectiveness of individualised homeopathic treatment for IBS. A three-armed trial was conducted which compared: usual care, homeopathic treatment plus usual care and supportive listening plus usual care. The primary outcome was change in irritable bowel symptom severity score between baseline and 26 weeks, calculated using ANCOVA. An interim ANCOVA adjusted for baseline IBS severity, age and employment status found no statistically significant difference between the three arms. However, a post-hoc test comparing homeopathic treatment plus usual care to usual care alone found a statistically significant difference in favour of homeopathic treatment. In addition, 62.5 percent of patients in the homeopathic treatment arm (compared to 25.0 percent of those in the usual care arm), achieved a clinically relevant change in irritable bowel symptom severity score, which indicates a promising effect for homeopathic treatment, though these results should be interpreted with caution due to the low number of participants in the study.

U2 - 10.1016/j.homp.2014.05.001

DO - 10.1016/j.homp.2014.05.001

M3 - Article

VL - 103

SP - 172

EP - 177

JO - Homeopathy: the Journal of the Faculty of Homeopathy

JF - Homeopathy: the Journal of the Faculty of Homeopathy

SN - 1475-4916

IS - 3

ER -