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Intramolecular epoxide ring opening cyclisation reactions involving guanidines

Research output: Contribution to journal › Article › peer-review

Standard Standard

Intramolecular epoxide ring opening cyclisation reactions involving guanidines. / Al-Shuhaib, Zainab; Arndt, Marcel; Dennis, Mark et al.
In: Tetrahedron, Vol. 73, No. 7, 16.02.2017, p. 845-852.

Research output: Contribution to journal › Article › peer-review

HarvardHarvard

Al-Shuhaib, Z, Arndt, M, Dennis, M, Evans, D, Jones, I, Leitmann, V, Murphy, P, Roberts, D, Rowles, R, Sadaghiani, YK, Thornhill, AJ, Nash, RJ, Hollinshead, J, Bartholomew, B, Tizzard, G & Coles, S 2017, 'Intramolecular epoxide ring opening cyclisation reactions involving guanidines', Tetrahedron, vol. 73, no. 7, pp. 845-852. https://doi.org/10.1016/j.tet.2016.12.065

APA

Al-Shuhaib, Z., Arndt, M., Dennis, M., Evans, D., Jones, I., Leitmann, V., Murphy, P., Roberts, D., Rowles, R., Sadaghiani, Y. K., Thornhill, A. J., Nash, R. J., Hollinshead, J., Bartholomew, B., Tizzard, G., & Coles, S. (2017). Intramolecular epoxide ring opening cyclisation reactions involving guanidines. Tetrahedron, 73(7), 845-852. https://doi.org/10.1016/j.tet.2016.12.065

CBE

Al-Shuhaib Z, Arndt M, Dennis M, Evans D, Jones I, Leitmann V, Murphy P, Roberts D, Rowles R, Sadaghiani YK, et al. 2017. Intramolecular epoxide ring opening cyclisation reactions involving guanidines. Tetrahedron. 73(7):845-852. https://doi.org/10.1016/j.tet.2016.12.065

MLA

Al-Shuhaib, Zainab et al. "Intramolecular epoxide ring opening cyclisation reactions involving guanidines". Tetrahedron. 2017, 73(7). 845-852. https://doi.org/10.1016/j.tet.2016.12.065

VancouverVancouver

Al-Shuhaib Z, Arndt M, Dennis M, Evans D, Jones I, Leitmann V et al. Intramolecular epoxide ring opening cyclisation reactions involving guanidines. Tetrahedron. 2017 Feb 16;73(7):845-852. Epub 2016 Dec 27. doi: 10.1016/j.tet.2016.12.065

Author

Al-Shuhaib, Zainab ; Arndt, Marcel ; Dennis, Mark et al. / Intramolecular epoxide ring opening cyclisation reactions involving guanidines. In: Tetrahedron. 2017 ; Vol. 73, No. 7. pp. 845-852.

RIS

TY - JOUR

T1 - Intramolecular epoxide ring opening cyclisation reactions involving guanidines

AU - Al-Shuhaib, Zainab

AU - Arndt, Marcel

AU - Dennis, Mark

AU - Evans, Daniel

AU - Jones, Iestyn

AU - Leitmann, Vera

AU - Murphy, Patrick

AU - Roberts, Dion

AU - Rowles, Richard

AU - Sadaghiani, Yones K.

AU - Thornhill, Andrew J.

AU - Nash, Robert J.

AU - Hollinshead, Jackie

AU - Bartholomew, Barbara

AU - Tizzard, Graham

AU - Coles, Simon

PY - 2017/2/16

Y1 - 2017/2/16

N2 - The cyclisation of N-allyl- and N-homoallylguanidines using DMDO leading to the formation of novel 5- and 6-membered guanidine heterocycles is reported. Several of the products formed displayed weak inhibition of glycosidase enzymes.

AB - The cyclisation of N-allyl- and N-homoallylguanidines using DMDO leading to the formation of novel 5- and 6-membered guanidine heterocycles is reported. Several of the products formed displayed weak inhibition of glycosidase enzymes.

KW - guanidines

KW - epoxides

KW - epoxidation

KW - DMDO

KW - iodocyclisations

KW - galactosidase inhibition

U2 - 10.1016/j.tet.2016.12.065

DO - 10.1016/j.tet.2016.12.065

M3 - Article

VL - 73

SP - 845

EP - 852

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 7

ER -