Longer Duration of Untreated Psychosis is associated with poorer outcomes for patients with Delusional Infestation
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- 2018 Longer duration of untreated psychosis
Accepted author manuscript, 566 KB, PDF document
- 2018 Longer duration
Final published version, 379 KB, PDF document
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DOI
We examined the association between the duration of untreated psychosis (DUP) and outcome for patients with delusional infestation (DI). This multi-centre international study included consecutive 211 patients. Illness severity was evaluated at first presentation and outcome was measured with the Clinical Global Impression scale (CGI) at base line and follow-up. A regression analysis showed a clear clinical and statistically significant association between shorter duration of untreated psychosis and better outcome at follow up. Patients with a DUP of less than 1 year showed a CGI-S change from 5.37 to 2.07; those with a DUP of 1-5 years a change from 5.48 to 2.59, and those with a DUP of above 5 years a change from 5.59 to 3.37. This difference of 1.1 CGI points between the groups resembles a clinically relevant difference in patient outcome Our results suggest that longer duration of untreated psychosis in patients with DI is associated with significantly less favourable clinical outcomes.
Original language | English |
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Pages (from-to) | 848-854 |
Journal | Acta Dermato-Venereologica |
Volume | 98 |
Issue number | 9 |
Early online date | 24 Jan 2018 |
DOIs | |
Publication status | Published - Sept 2018 |
Externally published | Yes |
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