Mycobacterium alvei (ω-1)-methoxy mycolic acids: Absolute stereochemistry and synthesis
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Electronic versions
Cells of Mycobacterium alvei are known to contain a unique set of mycolic acids with a (ω-1)-methoxy group; although the various enzymes in the biosynthesis of other types of mycolic acid have been widely studied, the biosynthetic route to this substituent is unclear. We now define the stereochemistry of the (ω-1)-methoxy fragment as R, and describe the synthesis of a major R-(ω-1)-methoxy-mycolic acid and its sugar esters, and of two natural M. alvei diene mycolic acids.
Keywords
- Mycobacterium, Alvei, Mycolic acid, (ω-1)-Methoxy, Synthesis
| Original language | English |
|---|---|
| Article number | 104977 |
| Number of pages | 1 |
| Journal | Chemistry and Physics of Lipids |
| Volume | 233 |
| Early online date | 20 Sept 2020 |
| DOIs | |
| Publication status | Published - Nov 2020 |