Mycobacterium alvei (ω-1)-methoxy mycolic acids: Absolute stereochemistry and synthesis
Allbwn ymchwil: Cyfraniad at gyfnodolyn › Erthygl › adolygiad gan gymheiriaid
Fersiynau electronig
Dolenni
Dangosydd eitem ddigidol (DOI)
Cells of Mycobacterium alvei are known to contain a unique set of mycolic acids with a (ω-1)-methoxy group; although the various enzymes in the biosynthesis of other types of mycolic acid have been widely studied, the biosynthetic route to this substituent is unclear. We now define the stereochemistry of the (ω-1)-methoxy fragment as R, and describe the synthesis of a major R-(ω-1)-methoxy-mycolic acid and its sugar esters, and of two natural M. alvei diene mycolic acids.
Allweddeiriau
| Iaith wreiddiol | Saesneg |
|---|---|
| Rhif yr erthygl | 104977 |
| Nifer y tudalennau | 1 |
| Cyfnodolyn | Chemistry and Physics of Lipids |
| Cyfrol | 233 |
| Dyddiad ar-lein cynnar | 20 Medi 2020 |
| Dynodwyr Gwrthrych Digidol (DOIs) | |
| Statws | Cyhoeddwyd - Tach 2020 |