Post-exercise hypotension after exercising in hypoxia with and without tart cherry supplementation

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  • Horiuchi_20241024_HAMB_revised_author_accepted_version

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    Embargo ends: 31/12/99

Background: This study investigated the effects of hypoxic exercise with and without tart cherry supplementation on post-exercise hypotension (PEH). Method: In a randomized order, 12 healthy young adults (9 men and 3 women) completed cycle exercise to exhaustion i) in normoxia without any supplementation (Norm), ii) in hypoxia (13% O2) with placebo (Hypo), and iii) in hypoxia with tart cherry supplementation (Hypo+TC). Supplements were supplied for 5 days pre-trial (TC was 200 mg anthocyanin per day for 4 days and 100 mg on day 5). Results: Cycle exercise total energy expenditure was greater in Norm than Hypo and Hypo+TC (P<0.001) with no difference between Hypo and Hypo+TC (P=0.41). Mean arterial pressure (MAP) decreased during recovery in all trials (main effect of time, P<0.001), with no difference in PEH between the trials (P>0.05, change (Δ) in MAP from pre-exercise at 60 min recovery, mean difference, Norm Δ-4.4 mmHg, Hypo Δ-6.1 mmHg, and Hypo+TC Δ-5.2 mmHg). Cardiac baroreflex sensitivity decreased during recovery in all trials (P<0.001) and was lower in Hypo than Norm and Hypo+TC (main effect of trial, P=0.02). Conclusion: Post-exercise hypotension was not increased after exercise in hypoxia, with or without tart cherry supplementation, compared to exercise in normoxia.
Original languageEnglish
JournalHigh Altitude Medicine and Biology
Publication statusAccepted/In press - 26 Oct 2024
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