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Preparation of an ABC tricyclic model of the cylindrospermopsin alkaloids via a biomimetically inspired pathway. / Murphy, P.J.; Evans, D.M.; Horton, P.N. et al.
In: RSC Advances, Vol. 4, No. 40, 28.04.2014, p. 20744-20751.

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Murphy PJ, Evans DM, Horton PN, Hursthouse MB. Preparation of an ABC tricyclic model of the cylindrospermopsin alkaloids via a biomimetically inspired pathway. RSC Advances. 2014 Apr 28;4(40):20744-20751. doi: 10.1039/C4RA03031A

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Murphy, P.J. ; Evans, D.M. ; Horton, P.N. et al. / Preparation of an ABC tricyclic model of the cylindrospermopsin alkaloids via a biomimetically inspired pathway. In: RSC Advances. 2014 ; Vol. 4, No. 40. pp. 20744-20751.

RIS

TY - JOUR

T1 - Preparation of an ABC tricyclic model of the cylindrospermopsin alkaloids via a biomimetically inspired pathway

AU - Murphy, P.J.

AU - Evans, D.M.

AU - Horton, P.N.

AU - Hursthouse, M.B.

PY - 2014/4/28

Y1 - 2014/4/28

N2 - Two tricyclic guanidine model compounds 28 and 29 have been prepared in 12 steps from 1,5-pentanediol using a biomimetic synthetic approach. The pivotal reaction in the sequence is a tethered Biginelli condensation between 21/22 and β-keto esters 23 and 24.

AB - Two tricyclic guanidine model compounds 28 and 29 have been prepared in 12 steps from 1,5-pentanediol using a biomimetic synthetic approach. The pivotal reaction in the sequence is a tethered Biginelli condensation between 21/22 and β-keto esters 23 and 24.

U2 - 10.1039/C4RA03031A

DO - 10.1039/C4RA03031A

M3 - Article

VL - 4

SP - 20744

EP - 20751

JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 40

ER -